Browsing by Author "Lavorato, Dina H."

Now showing 1 - 5 of 5
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    Allergies and major depression: a longitudinal community study
    (BioMed Central, 2009-01-26) Patten, Scott B.; Williams, Jeanne V.A.; Lavorato, Dina H.; Eliasziw, Michael
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    The effect of major depression on participation in preventive health care activities
    (BioMed Central, 2009-03-25) Patten, Scott B.; Williams, Jeanne V.A.; Lavorato, Dina H.; Eliasziw, Michael
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    A Longitudinal Community Study of Major Depression and Physical Activity
    (Elsevier, 2009) Patten, Scott B.; Williams, Jeanne V.A.; Lavorato, Dina H.; Eliasziw, Michael
    Background: The objective of this study was to determine whether major depressive episodes (MDE) are associated transitions between active and inactive recreational activity patterns. Methods: The data source was the Canadian National Population Health Survey (NPHS). The NPHS included a brief instrument to assess major depressive episodes and collected data on participation in recreational activities. In order to meaningfully categorize participation in recreational activities, the participation data was translated into overall estimated metabolic energy expenditure. A threshold of 1.5 kcal/kg/day was used to distinguish between active and inactive activity patterns. Proportional hazards models were used to compare the incidence of inactivity in initially active respondents with and without MDE and to compare the frequency of becoming active among initially inactive respondents with and without MDE. Results: For active respondents with MDE an elevated risk of transition into an inactive pattern was observed, adjusted Hazard Ratio (HR) = 1.6 (95% CI 1.2 – 1.9). However, MDE did not affect the probability of moving from an inactive to an active lifestyle, adjusted HR = 1.0 (95% CI 0.78-1.19). Conclusions: Major depressive episodes are associated with an increased risk of transition from an active to inactive pattern of activity.
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    Major Depression Is a Risk Factor for Shorter Time to First Cigarette Irrespective of the Number of Cigarettes Smoked Per Day: Evidence From a National Population Health Survey
    (Oxford Open, 2011) Khaled, Salma M.; Bulloch, Andrew G.; Williams, Jeanne V.A.; Lavorato, Dina H.; Patten, Scott B.
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    Major Depression, Antidepressant Medication and the Risk of Obesity
    (Karger, 2009) Patten, Scott B.; Williams, Jeanne V.A.; Lavorato, Dina H.; Brown, Lauren; McLaren, Lindsay; Eliasziw, Michael
    Background: Cross-sectional studies have reported an association between episodes of major depression (MDE) and obesity. The objective of this longitudinal analysis was to determine whether MDE increases the risk of becoming obese over a 10 year period. Method: We used data from the Canadian National Population Health Survey (NPHS), a longitudinal study of a representative cohort of household residents in Canada. The incidence of obesity, defined as a body mass index (BMI) of ≥ 30 kg/m2 was evaluated in respondents who were 18 years or older at the time of a baseline interview in 1994. MDE was assessed using a brief diagnostic instrument. Results: The risk of obesity was not elevated in association with MDE, either in unadjusted or covariate-adjusted analyses. The strongest predictor of obesity was a BMI in the overweight (but not obese) range. Effects were also seen for (younger) age, (female) sex, a sedentary activity pattern, low income and exposure to antidepressant medications. Unexpectedly, significant effects were seen for serotonin reuptake inhibiting antidepressants and venlafaxine, but not for tricyclic antidepressants nor antipsychotic medications. Conclusions: MDE does not appear to increase the risk of obesity. The cross-sectional associations that have been reported, albeit inconsistently, in the literature probably represent an effect of obesity on MDE risk. Pharmacologic treatment with antidepressants may be associated with an increased risk of obesity, and strategies to offset this risk may be useful in clinical practice.