Cumming School of Medicine
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The University of Calgary Faculty of Medicine was established in 1967 and renamed the Cumming School of Medicine in 2014. The Cumming School of Medicine is a national research leader in brain and mental health, chronic diseases and cardiovascular sciences.
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Browsing Cumming School of Medicine by Department "Critical Care Medicine"
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- ItemOpen AccessThe accuracy of pulse oximetry in emergency department patients with severe sepsis and septic shock: a retrospective cohort study(BioMed Central, 2010-05-05) Wilson, Ben J.; Cowan, Hamish J.; Lord, Jason A.; Zuege, Dan J.; Zygun, David A.
- ItemOpen AccessAdverse health behaviours are associated with depression and anxiety in multiple sclerosis: A prospective multisite study(SAGE PUBLICATIONS LTD, 2016) McKay, Kyla A.; Tremlett, Helen; Fisk, John D.; Patten, Scott B.; Fiest, Kirsten; Berrigan, Lindsay; Marrie, Ruth AnnBackground: Depression and anxiety are common among people with multiple sclerosis (MS), as are adverse health behaviours, but the associations between these factors are unclear. Objective: To evaluate the associations between cigarette smoking, alcohol use, and depression and anxiety in MS in a cross-Canada prospective study. Methods: From July 2010 to March 2011 we recruited consecutive MS patients from four MS clinics. At three visits over two years, clinical and demographic information was collected, and participants completed questionnaires regarding health behaviours and mental health. Results: Of 949 participants, 75.2% were women, with a mean age of 48.6 years; most had a relapsing-remitting course (72.4%). Alcohol dependence was associated with increased odds of anxiety (OR: 1.84; 95% CI: 1.32-2.58) and depression (OR: 1.53; 95% CI: 1.05-2.23) adjusting for age, sex, Expanded Disability Status Scale (EDSS), and smoking status. Smoking was associated with increased odds of anxiety (OR: 1.29; 95% CI: 1.02-1.63) and depression (OR: 1.37; 95% CI: 1.04-1.78) adjusting for age, sex, EDSS, and alcohol dependence. Alcohol dependence was associated with an increased incidence of depression but not anxiety. Depression was associated with an increased incidence of alcohol dependence. Conclusion: Alcohol dependence and smoking were associated with anxiety and depression. Awareness of the effects of adverse health behaviours on mental health in MS might help target counselling and support for those 'at risk'.
- ItemOpen AccessAnemia and red blood cell transfusion in neurocritical care(BioMed Central, 2009-06-11) Kramer, Andreas H.; Zygun, David A
- ItemOpen AccessAssessing Nociception by fMRI of the Human Spinal Cord: A Systematic Review(SAGE PUBLICATIONS LTD, 2015) Kolesar, Tiffany A.; Fiest, Kirsten M.; Smith, Stephen D.; Kornelsen, JenniferOBJECTIVE: To assess the use of fMRI of the spinal cord in measuring noxious stimulation. METHODS: The Scopus, Medline, EMBASE, and Web of Science databases were searched, along with the reference lists of included articles. Two independent reviewers screened abstracts, full-text articles, and extracted data. Original research was included if fMRI of the human spinal cord was used to measure responses to noxious stimulation. RESULTS: Of the 192 abstracts screened, 19 met the search criteria and were divided according to their focus: investigating pain responses (n = 6), methodology (n = 6), spinal cord injury (n = 2), or cognition-pain interactions (n = 5). All but one study appear to have observed activity in ipsilateral and dorsal gray matter regions in response to noxious stimuli, although contralateral or ventral activity was also widely observed. CONCLUSIONS: Although nociception can be investigated using spinal fMRI, establishing reliability, standardizing methodology, and reporting of results will greatly advance this field.
- ItemOpen AccessAssessment of the safety and feasibility of administering anti-pyretic therapy in critically ill adults: study protocol of a randomized trial(BioMed Central, 2012-03-12) Niven, Daniel J.; Léger, Caroline; Kubes, Paul; Stelfox, H. Tom; Laupland, Kevin B.
- ItemOpen AccessClinical review: Medication errors in critical care(BioMed Central, 2008-03) Moyen, Eric; Camiré, Eric; Stelfox, Henry Thomas
- ItemOpen AccessComparing the physical, psychological, social, and spiritual needs of patients with non-cancer and cancer diagnoses in a tertiary palliative care setting(2019-11-27) Bandeali, Suhair; des Ordons, Amanda Roze; Sinnarajah, AynharanOBJECTIVE: The purpose was to describe the physical, psychological, social, and spiritual needs of patients with non-cancer serious illness diagnoses compared to those of patients with cancer. METHOD: We conducted a retrospective chart review of all patients with a non-cancer diagnosis admitted to a tertiary palliative care unit between January 2008 and December 2017 and compared their needs to those of a matched cohort of patients with cancer diagnoses. The prevalence of needs within the following four main concerns was recorded and the data analyzed using descriptive statistics and content analysis: •Physical: pain, dyspnea, fatigue, anorexia, edema, and delirium•Psychological: depression, anxiety, prognosis, and dignity•Social: caregiver burden, isolation, and financial•Spiritual: spiritual distress. RESULTS: The prevalence of the four main concerns was similar among patients with non-cancer and cancer diagnoses. Pain, nausea/vomiting, fatigue, and anorexia were more prevalent among patients with cancer. Dyspnea was more commonly the primary concern in patients with non-cancer diagnoses (39%), who also had a higher prevalence of anxiety and concerns about dignity. Spirituality was addressed more often in patients with cancer. SIGNIFICANCE OF RESULTS: The majority of patients admitted to tertiary palliative care settings have historically been those with cancer. The tertiary palliative care needs of patients with non-cancer diagnoses have not been well described, despite the increasing prevalence of this population. Our description of the palliative care needs of patients with non-cancer diagnoses will help guide future palliative care for the increasing population of patients with non-cancer serious illness diagnoses.
- ItemOpen AccessComplications related to deep venous thrombosis prophylaxis in trauma: a systematic review of the literature(BioMed Central, 2010-01-06) Datta, Indraneel; Ball, Chad G.; Rudmik, Lucas; Hameed, S Morad; Kortbeek, John B
- ItemOpen AccessDeidentified dataset from Time spent formatting research manuscripts for submission annually(2018-10-21) Fiest, Kirsten M; Stelfox, Henry TData from journals studied to determine how long it takes to complete the formatting and submission process. No patient data is in this dataset. Data was generated by two research assistants who timed how long it took them to format and submit papers for publication to the top 10 general internal medicine journals. Other data came from publicly available websites.
- ItemOpen AccessDelayed esophageal perforation following lightning strike: a case report and review of the literature(BioMed Central, 2013-08-20) Figgis, Patricia; Alvarez, George F.
- ItemOpen AccessDelayed esophageal perforation following lightning strike: a case report and review of the literature(BioMed Central, 2012-08-20) Alvarez, George F.; Figgis, Patricia
- ItemOpen AccessDelirium in the Intensive Care Unit (ICU): a guide for patients and families(2018-05-15) Fiest, Kirsten; Rosgen, Brianna; Friesen, Allison; Herold, Karolina
- ItemOpen AccessDelirium severity and patient health outcomes: a systematic review and meta-analysis(2018-04-25) Rosgen, Brianna; Krewulak, Karla D.; Ely, E. Wesley; Stelfox, Henry Thomas; Fiest, Kirsten M.
- ItemOpen AccessDeterminants of non-adherence to disease-modifying therapies in multiple sclerosis: A cross-Canada prospective study(SAGE PUBLICATIONS LTD, 2017) McKay, Kyla A.; Tremlett, Helen; Patten, Scott B.; Fisk, John D.; Evans, Charity; Fiest, Kirsten; Campbell, Trudy; Marrie, Ruth AnnBackground: Poor adherence to the disease-modifying therapies (DMTs) for multiple sclerosis (MS) may attenuate clinical benefit. A better understanding of characteristics associated with non-adherence could improve outcomes. Objective: To evaluate characteristics associated with non-adherence to injectable DMTs. Methods: Consecutive patients from four Canadian MS Clinics were assessed at three time points over two years. Clinical and demographic information included self-reported DMT use, missed doses in the previous 30 days, health behaviors, and comorbidities. Non-adherence was defined as <80% of expected doses taken. We employed generalized estimating equations to examine characteristics associated with non-adherence at all time points with findings reported as adjusted odds ratios (OR). Results: In all, 485 participants reported use of an injectable DMT, of whom 107 (22.1%) were non-adherent over the study period. Non-adherence was associated with a lower Expanded Disability Status Scale score (0-2.5 vs 3.0-5.5, OR: 1.80; 95% confidence interval (CI): 1.06-3.04), disease duration (>= 5 vs < 5 years, OR: 2.23; 95% CI: 1.10-4.52), alcohol dependence (OR: 2.14; 95% CI: 1.23-3.75), and self-reported cognitive difficulties, measured by the Health Utilities Index-3 (OR: 1.55; 95% CI: 1.08-2.22). Conclusions: Nearly one-quarter of participants were non-adherent during the study. Alcohol dependence, perceived cognitive difficulties, longer disease duration, and mild disability status were associated with non-adherence. These characteristics may help healthcare professionals identify patients at greatest risk of poor adherence.
- ItemOpen AccessDeterminants of tracheostomy decannulation: an international survey(BioMed Central, 2008-02) Stelfox, Henry Thomas; Crimi, Claudia; Berra, Lorenzo; Noto, Alberto; Schmidt, Ulrich; Bigatello, Luca M; Hess, Dean
- ItemOpen AccessDeveloping a patient and family-centred approach for measuring the quality of injury care: a study protocol(BioMed Central, 2013-01-27) Stelfox, H. Thomas; Boyd, Jamie M.; Straus, Sharon E.; Gagliardi, Anna R.
- ItemOpen AccessThe epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care units(BioMed Central, 2008-12-18) Stelfox, Henry Thomas; Ahmed, Sofia B; Khandwala, Farah; Zygun, David; Shahpori, Reza; Laupland, Kevin B.
- ItemOpen AccessICU Delirium Search Strategy(2016) Fiest, Kirsten
- ItemOpen AccessIncidence, prevalence, and occurrence rate of infection among adults hospitalized after traumatic brain injury: study protocol for a systematic review and meta-analysis(BioMed Central, 2013-08-24) Scott, Brittney NV; Roberts, Derek J; Robertson, Helen Lee; Kramer, Andreas H; Laupland, Kevin B; Ousman, Shalina S; Kubes, Paul; Zygun, David A
- ItemOpen AccessIntensive care unit-acquired urinary tract infections in a regional critical care system(BioMed Central, 2005-01) Laupland, Kevin B.; Bagshaw, S. M.; Gregson, D. B .; Kirkpatrick, Andrew W.; Ross, T.; Church, D. L.
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