Legacy Theses
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University of Calgary masters and doctoral theses submitted in paper format prior to the electronic thesis and dissertation program.
University of Calgary graduate alumni can make their thesis publicly available in PRISM by contacting digitalservices@ucalgary.libanswers.com
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Browsing Legacy Theses by Department "Cardiovascular & Respiratory Sciences"
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Item Open Access A murine model of emery-dreifuss muscular dystrophy(2003) Grattan, Michael James; Giles, Wayne R.Item Open Access A novel approach to mitral flow(1995) MacRae, Jennifer Marie; Tyberg, John V.Item Open Access A study of the effects of left ventricular contractility and coronary tone on coronary flow dynamics using wave intensity analysis(2001) Sun, Yi-Hui; Tyberg, John V.Item Open Access Age-dependent effects of furosemide on cardiovascular control in conscious lambs(1999) Thomson, Julie J.; Smith, Francine G.Item Open Access Alpha adrenoceptors and their signal transduction pathways in vascular smooth muscle(1996) Li, Xiao-Fang; Triggle, Chris R.Item Open Access Alterations in current density and transmural regional heterogeneity of cardiac repolarization K+ currents in left ventricular hypertrophy(2000) Geonzon, Radzfel; Duff, Henry J.Item Open Access Application of the reservoir-wave approach to the renal circulation(2012) Handkamer, Kristen Claire; Tyberg, John V.The reservoir-wave approach provided the idea that systemic vascular resistance could be modeled as several component resistors arranged in series. The purpose of this investigation was to apply the reservoir-wave approach to the renal circulation and examine how a renal venous constriction (RVC) or a renal arterial infusion of vasoactive agents into one kidney altered conductance, P oo, and series resistances. Endothelin-1 and Angiotensin 11 reduced conductance to 39.6 ± 5.1 and 64.4 ± 4.3%; total renal resistance increased but arterial reservoir resistance decreased to 64.8 ± 6.3 and 80.0 ± 6.1 % of the control respectively. Endothelin-1 and Angiotensin II also increased Poo by 14.5 ± 2.7 and l 0.2 ± 3.6 mmHg, and the microcirculatory plus venous resistance to 187.2 ± 21.0 and 180.0 ± 35.8% ofthe control respectively. RVC increased conductance to I 12.3 ± 4.4% of the control, in apparent compensation. The reservoir-wave approach is applicable to the renal circulation and its use in subsequent investigations is warranted.Item Open Access Architecture of the asthmatic lung(1999) Boser, Stacey; Green, FrancisItem Open Access Assessment of left atrial mechanics and energetics in dogs using wave intensity analysis(2006) Hobson, Tracy Nicole; Tyberg, John V.Item Open Access Assessment of left ventricular diastolic suction using wave-intensity analysis(2003) Jalali, Fereshteh; Tyberg, John V.Left ventricular diastolic suction (LV DS) is defined as the property of the LV to refill itself during early diastole, independent of any force from the left atrium (LA). Two different mechanisms have been developed to explain this phenomenon. The first mechanism relates DS to the decrease in L V elastance. The second theory, relates DS to negative L V pressure, suggesting that the smaller the end-systolic volume, the greater the DS. In an attempt to reconcile these two mechanisms, wave-intensity analysis was used. The purpose of this study was to illustrate that Iw-BE (L V generated backward expansion wave) depends on both decreasing elastance and the L Vend-systolic volume. It was found that the energy ofLV DS is inversely proportional to -c and LV end-systolic volume. From these data a 3-D plot was formed demonstrating the non-linear dependence of L V DS on both of these variables.Item Open Access Biochemcial and functional studies of phoshorylation of cardiac ryanodine receptor by calcium/calmodulin dependent protein kinase II(2007) Zhong, Guo-Feng; Chen, S. R. WayneItem Open Access Ca2+ calmodulin-dependent protein kinase II (camk II) dependent short-term synaptic plasticity between identified lymnaea neurons(2007) Hassan, Atiq Ul; Syed, Naweed I.Item Open Access Cardiac function during mechanical ventilation in a canine model of oleic acid-induced acute lung injury(2008) Mitchell, Jamie R.; Tyberg, John V.Item Open Access Cardiac muscle function after coronary artery ligation in rat(2002) Davidoff, Allen Warren; ter Keurs, Henk E.D.J.Item Open Access Cellular basis of angiotensin II-induced contraction in the rat tail artery: The role of endothelium and endothelin-1(1999) Jiang, Yanfen; Triggle, Chris R.Item Open Access Cerebral blood flow responses to sustained alterations in end-tidal PO2 and PCO2 in humans(2004) Vantanajal, Jimmy S.; Poulin, Marc J.The techniques of transcranial Doppler ultrasound and dynamic end-tidal forcing were used to study the dynamics of the middle cerebral artery peak flow velocity (V P) (i.e. index of cerebral blood flow) response to 60 min of sustained isocapnic hypoxia, isocapnic hyperoxia, euoxic hypocapnia, and euoxic hypercapnia in humans. Each protocol involved two 60-min interventions, with a 60-min recovery period between tests. Peak flow velocity increased significantly during hypoxia (14.7%) and decreased during hyperoxia (11.8%). During hypercapnia, VP increased significantly (33.6%) and remained elevated. There was no evidence of adaptation during these protocols. However, a significant adaptation was observed during hypocapnia. After an initial decrease (39%), VP increased significantly and stabilized at 25.2% below baseline. This adaptive component was found to be significantly faster during the second intervention. There were no significant differences between the first and second intervention for the remaining protocols.Item Open Access Item Open Access Chloride movement during calcium uptake into the sarcoplasmic reticulum of cardiac and smooth muscle(1997) Pollock, Natashka S.; Kargacin, Gary J.Item Open Access Comparison of delayed rectifier potassium current in coronary artery and portal vein smooth muscle cells(1998) Sontag, David Patrick; Cole, William C.Item Open Access Conditions for cardiac muscle myosin regulatory light chain phosphorylation(2000) Willis, Janine Corinth; MacIntosh, Brian R.