The Neuroanatomical Correlates of Impaired Position Sense After Stroke
Date
2013-10-02
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Proprioception describes our sense of self-position and movement without vision. It plays a key role in the production and control of movement. Affected in 50% of stroke patients, impairment in proprioception is correlated with poor motor recovery, functional outcomes, and extended hospitalization. Proprioception-targeted rehabilitation is lacking. To contribute to improved understanding of the anatomical regions underlying proprioception, this study aimed to identify brain areas responsible for impaired position sense post-stroke. Voxel-based lesion-symptom mapping compared lesion location and performance on quantitative robotic position sense assessment. This and region of interest analyses revealed that the hypothesized areas: the thalamus; posterior limb of the internal capsule; postcentral gyrus; posterior parietal association area were associated with poor position sense in addition to non-hypothesized areas: insula; lingual, inferior frontal, superior temporal, and middle temporal gyri. Position sense appears to be a multi-dimensional construct, processed via a distributed network of brain regions.
Description
Keywords
Neuroscience
Citation
Findlater, S. (2013). The Neuroanatomical Correlates of Impaired Position Sense After Stroke (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/28256