Validation of the Comprehensive Hierarchical Evaluation of Disability based on Activity Limitations (miFunction) Scale: A Pilot Study

Date
2014-04-04
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Abstract
Background: A reliable measure of deficits following stroke is crucial in the measurement of the outcome of a therapeutic stroke trial. The modified Rankin Scale (mRS) is currently the most widely used primary outcome measure in acute stroke trials despite substantial interobserver variability, which impairs outcome assessment and reduces the power of clinical trials. In 2000, the World Health Organization (WHO) developed a patient-centered, International Classification of Functioning, Disability and Health (ICF). Guided by the ICF, stroke researchers and clinicians at the University of Calgary developed a comprehensive, hierarchical assessment tool (miFunction) to address the shortcomings of the mRS and deliver a more thorough understanding of disability following stroke as it is now defined. Methods: The initial validation of miFunction involved an assessment of inter-observer reliability (Kappa Statistic) as well as its convergent validation (Pearson Correlation Coefficient) against the mRS. Participants were recruited from a population of stroke survivors at an outpatient stroke prevention clinic in Calgary, Alberta and were eligible for inclusion to the study if they had been diagnosed with stroke within 60 days. A sample size of 30 was the target and was achieved over the course of 5 months in 2013 Results: Although the results demonstrated only moderate inter-observer agreement (k= 0.585, p<.005), almost perfect correlation between miFunction and mRS was established (r=0.821, p<0.05). Discussion: miFunction has demonstrated a strong ability to assess disability following stroke, though there remains work to be done to improve its inter-observer reliability. This work must further consider the language used for the assessment questions so as to avoid ambiguity, confusion or misinterpretation.
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Keywords
Nursing, Psychometrics
Citation
Burley, T. (2014). Validation of the Comprehensive Hierarchical Evaluation of Disability based on Activity Limitations (miFunction) Scale: A Pilot Study (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/28627