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Cerebral Blood Flow, Fitness and Behaviour Changes With a High Intensity, Socially Engaging Physical Activity Program for Young Adults With Autism Spectrum Disorder

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Advisor
Werthner, Dr. Penny
Author
Wickenheiser, Hayley
Committee Member
MacQueen, Dr. Glenda
Bray, Dr. Signe
Legg, David
Other
AUTISM
EXERCISE
CEREBRAL BLOOD FLOW
Subject
Education--Health
Education--Physical
Education--Sciences
Recreation
Social Work
Physiology
Mental Health
Recreation
Rehabilitation and Therapy
Psychology--Behavioral
Psychology--Physiological
Psychology--Social
Type
Thesis
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Abstract
The effects of a moderate to vigorous physical activity (MVPA) intervention on cerebral blood flow (CBF), fitness, and motor competence in young adults 18-35 with Autism Spectrum Disorder (ASD) were examined. Thirteen male and female participants underwent a one-hour weekly supervised, and a 30 minute 3 x weekly unsupervised, MVPA intervention. Arterial spin labeling (ASL), fitness testing, and diagnostic measurements gauged changes in CBF, fitness, and behaviors respectively. Statistical significance (p<0.05) was found in the Autism Diagnostic Observation Schedule (ADOS II) (pre mean=14.58, sd 4.38, n=12, post mean= 12.58, sd 4.17, n=12, p value=0.03) and wall sits (pre mean= 27.7s, sd 24.57, n=11, post mean= 42.3s, sd 23.98, n=11, p-value=0.04). CBF decreased insignificantly (p=0.62), and did not correlate with increases in NIRS (p=0.38) or aerobic fitness (p=0.30). The small increase in total Hb, using NIRS, suggests regional vs. global differences. The effectiveness of exercise in ASD requires more research.
Corporate
University of Calgary
Faculty
Graduate Studies
Doi
http://dx.doi.org/10.5072/PRISM/25243
Uri
http://hdl.handle.net/11023/3196
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