Enhanced Electrogastrography Using Transcutaneous Intraluminal Impedance Measurements (TIIM)
Abstract
Gastric motility and gastric emptying rates have been implicated in the symptoms of functional dyspepsia and gastroparesis. The current gold standard to assess gastric emptying is scintigraphy, which is limited by standardization and radiation concerns. This highlights the need for a novel method of assessing gastric motility.
Transcutaneous Intraluminal Impedance Measurement (TIIM) is a novel method of assessing gastric motility. By measuring the dynamics of a known signal emitted from a battery-powered gastric retentive oscillator within the stomach, gastric motility can be quantified.
In an eight-dog sham comparison study, TIIM was compared to force transducers implanted on the stomach. Two assessment metrics demonstrated statistically significant Pearson correlation coefficients between active TIIM pills and the force transducers (p<0.01, p<0.05), but not when TIIM pills were replaced by sham deactivated pills (p>0.1, p>0.1). A novel portable TIIM receiver was also proposed and tested in the lab to facilitate future ambulatory studies.
Description
Keywords
Engineering--Biomedical
Citation
Poscente, M. D. (2016). Enhanced Electrogastrography Using Transcutaneous Intraluminal Impedance Measurements (TIIM) (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25899