Preterm Birth: Understanding Temporal Changes in Anxiety and Depression Measures
Abstract
Background: This study aimed to understand whether there is a pattern of change in levels of anxiety and depression between the second and third trimesters of pregnancy that are associated with a risk of PTB. Chronic stress was assessed as a potential modifier of the relationship.
Methods: This study conducted a secondary data analysis on the All Our Babies prospective cohort. Logistic regression modeling was used to analyze the data.
Results: A worsening of anxiety during pregnancy increased the odds of preterm delivery (OR 2.70, 95% CI 1.28, 5.69; p=0.009). An improvement in anxiety reduced the odds of PTB (OR 0.96, 95% CI 0.94, 0.98; p=<0.001). Consistently low depression decreased the odds of PTB (OR 0.65, 95% CI 0.45, 0.96; p=0.029). Chronic stress did not modify any of these relationships.
Conclusions: Efforts should be made to replicate these results in a cohort with a larger sample size.
Description
Keywords
Epidemiology, Mental Health, Obstetrics and Gynecology, Public Health
Citation
Doktorchik, C. (2017). Preterm Birth: Understanding Temporal Changes in Anxiety and Depression Measures (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/27423