Based on Winkler method, pipe can be simplified as a beam, while pipe-soil interaction can be represented by soil springs in the axial, horizontal and vertical direction. Pipe deflection and resultant forces are related to each other by coefficient K in the equation F=Kδ, where F is the resultant force and δ is the pipe displacement. This project studies pipe-soil interaction for pipelines buried in clay and sand subjected to pipeline displacement in oblique direction. The objective is to quantify the effect of soil parameters on coefficient K and maximum soil resistance. Pipe-soil behavior has been studied using the finite element software ABAQUS/CAE. There were totally 48 models with varying soil parameters, pipe burial depth and pipe-soil interaction friction to investigate the effect of each variable on pipe-soil behavior. The results have been presented in normalized force-displacement plots to identify the parameters which affect the soil resistance most. In addition they have been compared to the analytical results from ALA (2001) and proposed failure envelopes in previous studies. The results show that the maximum normal force per unit length depends on the type of soil surrounding the pipe. By comparing all the results pipe burial depth, soil cohesion, friction and dilation angles were found to have a significant effect on pipe-soil interaction and can considerably increase the maximum soil resistance.