The University of Calgary Faculty of Medicine was established in 1967 and renamed the Cumming School of Medicine in 2014. The Cumming School of Medicine is a national research leader in brain and mental health, chronic diseases and cardiovascular sciences.

Cumming School of Medicine

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  • Effectiveness of a standardized electronic admission order set for acute exacerbation of chronic obstructive pulmonary disease 

    Pendharkar, Sachin R.; Ospina, Maria B.; Gadotti, D. A.; Hirani, Naushad; Graham, Jim Allen; Faris, Peter D.; Bhutani, Mohit; Leigh, Richard A.; Mody, Christopher H.; Strickland, Michael K. (BMC Pulmonary Medicine, Cumming School of Medicine, Community Health Sciences, Medicine, University of Calgary,, Publisher's version, 2018-05-30)
    Background: Variation in hospital management of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may prolong length of stay, increasing the risk of hospital-acquired complications and ...
  • Analysis of GPCR/ion channel interactions 

    Altier, Christophe; Zamponi, Gerald W. (Springer, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary, 2011-01-01)
    Voltage-gated calcium channels are key regulators of calcium homeostasis in excitable cells. A number of cellular signaling pathways serve to fine tune calcium channel activity, including the activation of G protein-coupled ...
  • All quiet on the neuronal front: NMDA receptor inhibition by prion protein 

    Steele, Andrew D. (The Rockefeller University Press, California Institute of Technology, 2008-04-28)
    The normal function of the prion protein (PrP)--the causative agent of mad cow or prion disease--has long remained out of reach. Deciphering PrP's function may help to unravel the complex chain of events triggered by PrP ...
  • Reciprocal regulation between voltage-gated calcium channels and calmodulin 

    Zamponi, Gerald W. (Cellscience, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary, 2008-06-01)
    Calcium entry via voltage gated calcium channels is subject to negative feedback regulation via a calcium dependent inactivation process. The features of calcium dependent inactivation vary with calcium channel subtype ...
  • Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice 

    Grant, Andrew Douglas; Cottrell, Graeme S.; Amadesi, Silva; Trevisani, Marcello; Nicoletti, Paola; Materazzi, Serena; Altier, Christophe; Cenac, Nicolas S.; Zamponi, Gerald W.; Bautista-Cruz, Francisco; Lopez, Carlos Barajas; Joseph, Elizabeth K.; Levine, Jon David; Liedtke, Wolfgang B.; Vanner, Stephen J.; Vergnolle, Nathalie; Geppetti, Pierangelo; Bunnett, Nigel W. (Blackwell Publishing, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary,, 2006-11-23)
    Exacerbated sensitivity to mechanical stimuli that are normally innocuous or mildly painful (mechanical allodynia and hyperalgesia) occurs during inflammation and underlies painful diseases. Proteases that are generated ...
  • Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants 

    Heron, Sarah E.; Khosravani, Houman; Varela, Diego L.; Bladen, Chris; Williams, Tristiana C.; Newman, Michelle R.; Scheffer, Ingrid; Berkovic, Samuel F.; Mulley, John C.; Zamponi, Gerald W. (Wiley-Liss, Inc., Cumming School of Medicine, Physiology & Pharmacology, University of Calgary,, 2007-08-14)
    The relationship between genetic variation in the T-type calcium channel gene CACNA1H and childhood absence epilepsy is well established. The purpose of this study was to investigate the range of epilepsy syndromes for ...
  • Epilepsy genetics: yet more exciting news 

    Lowenstein, Daniel Hays; Messing, Robert O. (Wiley-Liss, Inc., University of California,, 2007-12-01)
  • Presynaptic calcium channels: structure, regulators, and blockers 

    Kisilevsky, Alexandra E.; Zamponi, Gerald W. (Springer, Cumming School of Medicine, Pathology & Laboratory Medicine, 2008-01-06)
    The central and peripheral nervous systems express multiple types of ligand and voltage-gated calcium channels (VGCCs), each with specific physiological roles and pharmacological and electrophysiological properties. The ...
  • Trafficking and regulation of neuronal voltage-gated calcium channels 

    Jarvis, Scott E.; Zamponi, Gerald W. (Elsevier, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary,, 2007-07-12)
    The importance of voltage-gated calcium channels is underscored by the multitude of intracellular processes that depend on calcium, notably gene regulation and neurotransmission. Given their pivotal roles in calcium (and ...
  • Use 'em and lose 'em-activity-induced removal of calcium channels from the plasma membrane 

    Varela, Diego L.; Zamponi, Gerald W. (Elsevier Inc., Cumming School of Medicine, Cell Biology & Anatomy, Physiology & Pharmacology, University of Calgary,, 2007-08-16)
    Calcium influx via L-type (Cav1.2 and Cav1.3) calcium channels is tightly regulated to ensure optimal intracellular calcium levels. Although much is known about acute modulation of these channels by second messengers, the ...

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