Recent Submissions

  • METRICS: a pattern language of scholarship in medical education 

    Ellaway, Rachel H.; Topps, David A. (Cumming School of Medicine, Other, University of Calgary, Publisher's version, 2017-11-07)
    Scholarly activity in health professions education has been growing steadily but despite the broad interest, quite what is considered to be scholarly activity in medical education has remained vague. Boyer’s classes of ...
  • Abstract booklet from the 2019 Sebastian K. Littmann Research Day 

    Patten, Scott B. (Cumming School of Medicine, University of Calgary, 2019-03-01)
  • Application of immobilized ATP to the study of NLRP inflammasomes 

    Liao, Kuo Chieh; Sandall, Christina F.; Carlson, David A.; Ulke-Lemée, Annegret; Platnich, Jaye; Hughes, Philip Floyd; Muruve, Daniel A.; Haystead, Timothy Arthur James; MacDonald, Justin Anthony (Cumming School of Medicine, Biochemistry & Molecular Biology, University of Calgary, Duke University, 2019-01-11)
    The NLRP proteins are a subfamily of the NOD-like receptor (NLR) innate immune sensors that possess an ATP-binding NACHT domain. As the most well-studied member, NLRP3 can initiate the assembly process of a multiprotein ...
  • Effects of phosphorylation on the NLRP3 inflammasome 

    Sandall, Christina F.; MacDonald, Justin Anthony (Cumming School of Medicine, Biochemistry & Molecular Biology, University of Calgary, 2019-03-05)
    The pyrin domain containing Nod-like receptors (NLRPs) are a family of pattern recognition receptors known to regulate an array of immune signaling pathways. Emergent studies demonstrate the potential for regulatory control ...
  • Targeting Pim kinases and DAPK3 to control hypertension 

    Carlson, David A.; Singer, Miriam R.; Sutherland, Cindy; Redondo, Clara; Alexander, Leila T.; Hughes, Philip Floyd; Knapp, Stefan; Gurley, Susan B.; Sparks, Matthew A.; MacDonald, Justin Anthony; Haystead, Timothy Arthur James (Cumming School of Medicine, Biochemistry & Molecular Biology, University of Calgary, Duke University Medical Center, University of Oxford, 2018-07-04)
    Sustained vascular smooth muscle hypercontractility promotes hypertension and cardiovascular disease. The etiology of hypercontractility is not completely understood. New therapeutic targets remain vitally important for ...
  • Young children in different linguistic environments: A multimodal neuroimaging study of the inferior frontal gyrus 

    Thieba, Camilia; Long, Xiangyu; Dewey, Deborah; Lebel, Catherine A. (Cumming School of Medicine, Community Health Sciences, Paediatrics, Radiology, University of Calgary, 2018-07-11)
    Magnetic resonance imaging (MRI) studies show that bilingual adults display structural and functional brain alterations, especially in the inferior frontal gyrus (IFG), dependent on when they learned their second language. ...
  • Brain white matter structure and language ability in preschool-aged children 

    Walton, Matthew; Dewey, Deborah; Lebel, Catherine A. (Cumming School of Medicine, Radiology, University of Calgary, Post-print, 2018-01)
    Brain alterations are associated with reading and language difficulties in older children, but little research has investigated relationships between early language skills and brain white matter structure during the preschool ...
  • The Prevalence and Incidence of Dementia: a Systematic Review and Meta-analysis 

    Fiest, Kirsten M.; Jette, Nathalie; Roberts, Jodie I.; Maxwell, Colleen J.; Smith, Eric E.; Black, Sandra E.; Blaikie, Laura; Cohen, Adrienne; Day, Lundy; Holroyd-Leduc, Jayna; Kirk, Andrew; Pearson, Dawn; Pringsheim, Tamara; Venegas-Torres, Andres; Hogan, David B. (CAMBRIDGE UNIV PRESS, Cumming School of Medicine, Critical Care Medicine, https://www.cambridge.org/core/services/open-access-policies, Published version, 2016)
    Introduction: Dementia is a common neurological condition affecting many older individuals that leads to a loss of independence, diminished quality of life, premature mortality, caregiver burden and high levels of healthcare ...
  • The Prevalence and Incidence of Dementia with Lewy Bodies: a Systematic Review 

    David B. Hogan, Kirsten M. Fiest, Jodie I. Roberts, Colleen J. Maxwell, Jonathan Dykeman, Tamara Pringsheim, Thomas Steeves, Eric E. Smith, Dawn Pearson, Nathalie Jetté (CAMBRIDGE UNIV PRESS, Cumming School of Medicine, Critical Care Medicine, https://www.cambridge.org/core/services/open-access-policies, Published version, 2016)
    Background Population-based prevalence and incidence studies are essential for understanding the societal burden of dementia with Lewy bodies (DLB). Methods The MEDLINE and EMBASE databases were searched to identify ...
  • The Prevalence and Incidence of Frontotemporal Dementia: a Systematic Review 

    Hogan, David B.; Jette, Nathalie; Fiest, Kirsten M.; Roberts, Jodie I.; Pearson, Dawn; Smith, Eric E.; Pamela Roach; Kirk, Andrew; Pringsheim, Tamara; Maxwell, Colleen J. (CAMBRIDGE UNIV PRESS, Cumming School of Medicine, Critical Care Medicine, https://www.cambridge.org/core/services/open-access-policies, Published version, 2016)
    Background Population-based prevalence and incidence studies are essential for understanding the burden of frontotemporal dementia (FTD). Methods The MEDLINE and EMBASE databases were searched to identify population-based ...

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