Recent Submissions

  • Testing the feasibility of eliciting preferences for health states from adolescents using direct methods 

    Lau, Ryan; Crump, R. Trafford; Cox, Elizabeth D.; Currie, Gillian R.; Panepinto, Julie Ann (BioMed Central Ltd., Cumming School of Medicine, Surgery, University of Calgary, 2018-06-22)
    Measuring adolescents' preferences for health states can play an important role in evaluating the delivery of pediatric healthcare. However, formal evaluation of the common direct preference elicitation methods for health ...
  • Case report: Diffuse hyperplastic perilobar nephroblastomatosis complicated by a unilateral Wilms tumour: diagnosis, treatment and follow-up 

    Gao, Bruce; Nzekwu, Emeka; Spaner, Shelley Jane; Cook, Anthony (BioMed Central Ltd., Cumming School of Medicine, Radiology, Surgery, University of Calgary,, 2018-06-19)
    Nephroblastomatosis is an uncommon pathologic process characterized by the presence of persistent embryonic nephrogenic rests. Progression to Wilms tumour occurs in an estimated 35% of patients. Cure rates are based on ...
  • Effectiveness of a standardized electronic admission order set for acute exacerbation of chronic obstructive pulmonary disease 

    Pendharkar, Sachin R.; Ospina, Maria B.; Gadotti, D. A.; Hirani, Naushad; Graham, Jim Allen; Faris, Peter D.; Bhutani, Mohit; Leigh, Richard A.; Mody, Christopher H.; Strickland, Michael K. (BMC Pulmonary Medicine, Cumming School of Medicine, Community Health Sciences, Medicine, University of Calgary,, Publisher's version, 2018-05-30)
    Background: Variation in hospital management of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may prolong length of stay, increasing the risk of hospital-acquired complications and ...
  • Analysis of GPCR/ion channel interactions 

    Altier, Christophe; Zamponi, Gerald W. (Springer, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary, 2011-01-01)
    Voltage-gated calcium channels are key regulators of calcium homeostasis in excitable cells. A number of cellular signaling pathways serve to fine tune calcium channel activity, including the activation of G protein-coupled ...
  • All quiet on the neuronal front: NMDA receptor inhibition by prion protein 

    Steele, Andrew D. (The Rockefeller University Press, California Institute of Technology, 2008-04-28)
    The normal function of the prion protein (PrP)--the causative agent of mad cow or prion disease--has long remained out of reach. Deciphering PrP's function may help to unravel the complex chain of events triggered by PrP ...
  • Reciprocal regulation between voltage-gated calcium channels and calmodulin 

    Zamponi, Gerald W. (Cellscience, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary, 2008-06-01)
    Calcium entry via voltage gated calcium channels is subject to negative feedback regulation via a calcium dependent inactivation process. The features of calcium dependent inactivation vary with calcium channel subtype ...
  • Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice 

    Grant, Andrew Douglas; Cottrell, Graeme S.; Amadesi, Silva; Trevisani, Marcello; Nicoletti, Paola; Materazzi, Serena; Altier, Christophe; Cenac, Nicolas S.; Zamponi, Gerald W.; Bautista-Cruz, Francisco; Lopez, Carlos Barajas; Joseph, Elizabeth K.; Levine, Jon David; Liedtke, Wolfgang B.; Vanner, Stephen J.; Vergnolle, Nathalie; Geppetti, Pierangelo; Bunnett, Nigel W. (Blackwell Publishing, Cumming School of Medicine, Physiology & Pharmacology, University of Calgary,, 2006-11-23)
    Exacerbated sensitivity to mechanical stimuli that are normally innocuous or mildly painful (mechanical allodynia and hyperalgesia) occurs during inflammation and underlies painful diseases. Proteases that are generated ...
  • Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants 

    Heron, Sarah E.; Khosravani, Houman; Varela, Diego L.; Bladen, Chris; Williams, Tristiana C.; Newman, Michelle R.; Scheffer, Ingrid; Berkovic, Samuel F.; Mulley, John C.; Zamponi, Gerald W. (Wiley-Liss, Inc., Cumming School of Medicine, Physiology & Pharmacology, University of Calgary,, 2007-08-14)
    The relationship between genetic variation in the T-type calcium channel gene CACNA1H and childhood absence epilepsy is well established. The purpose of this study was to investigate the range of epilepsy syndromes for ...
  • Epilepsy genetics: yet more exciting news 

    Lowenstein, Daniel Hays; Messing, Robert O. (Wiley-Liss, Inc., University of California,, 2007-12-01)
  • Presynaptic calcium channels: structure, regulators, and blockers 

    Kisilevsky, Alexandra E.; Zamponi, Gerald W. (Springer, Cumming School of Medicine, Pathology & Laboratory Medicine, 2008-01-06)
    The central and peripheral nervous systems express multiple types of ligand and voltage-gated calcium channels (VGCCs), each with specific physiological roles and pharmacological and electrophysiological properties. The ...

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