• A multi-center, randomized, 12-month, parallel-group, feasibility study to assess the acceptability and preliminary impact of family navigation plus usual care versus usual care on attrition in managing pediatric obesity: a study protocol 

  Ball, Geoff D. C.; O’Neill, Marcus G.; Noor, Rafat; Alberga, Angela; Azar, Rima; Buchholz, Annick; Enright, Michelle; Geller, Josie; Ho, Josephine; Holt, Nicholas L.; Lebel, Tracy; Rosychuk, Rhonda J.; Tarride, Jean-Eric; Zenlea, Ian (2023-01-23)

  Abstract Background Pediatric obesity management can be successful, but some families discontinue care prematurely (i.e., attrition), limiting treatment impact. Attrition is ...

• Parkin coregulates glutathione metabolism in adult mammalian brain 

  El Kodsi, Daniel N.; Tokarew, Jacqueline M.; Sengupta, Rajib; Lengacher, Nathalie A.; Chatterji, Ajanta; Nguyen, Angela P.; Boston, Heather; Jiang, Qiubo; Palmberg, Carina; Pileggi, Chantal; Holterman, Chet E.; Shutinoski, Bojan; Li, Juan; Fehr, Travis K.; LaVoie, Matthew J.; Ratan, Rajiv R.; Shaw, Gary S.; Takanashi, Masashi; Hattori, Nobutaka; Kennedy, Christopher R.; Harper, Mary-Ellen; Holmgren, Arne; Tomlinson, Julianna J.; Schlossmacher, Michael G. (2023-01-23)

  Abstract We recently discovered that the expression of PRKN, a young-onset Parkinson disease-linked gene, confers redox homeostasis. To further examine the protective effects of parkin in an oxidative stress ...

• Preoperative hemoglobin and perioperative blood transfusion in major head and neck surgery: a systematic review and meta-analysis 

  Ali, Munib; Dort, Joseph C.; Sauro, Khara M. (2023-01-24)

  Abstract Background There is a growing concern with inappropriate, excessive perioperative blood transfusions. Understanding the influence of low preoperative hemoglobin (Hgb) ...

• The use of machine learning and deep learning techniques to assess proprioceptive impairments of the upper limb after stroke 

  Hossain, Delowar; Scott, Stephen H.; Cluff, Tyler; Dukelow, Sean P. (2023-01-27)

  Abstract Background Robots can generate rich kinematic datasets that have the potential to provide far more insight into impairments than standard clinical ordinal scales. ...

• Effect of mobile application types on stroke rehabilitation: a systematic review 

  Szeto, Stephen G.; Wan, Hoyee; Alavinia, Mohammad; Dukelow, Sean; MacNeill, Heather (2023-01-24)

  Abstract Background Stroke is a significant contributor of worldwide disability and morbidity with substantial economic consequences. Rehabilitation is a vital component of ...

• Towards conceptualizing patients as partners in health systems: a systematic review and descriptive synthesis 

  Vanstone, Meredith; Canfield, Carolyn; Evans, Cara; Leslie, Myles; Levasseur, Mary A.; MacNeil, Maggie; Pahwa, Manisha; Panday, Janelle; Rowland, Paula; Taneja, Shipra; Tripp, Laura; You, Jeonghwa; Abelson, Julia (2023-01-25)

  Abstract Background With the sharp increase in the involvement of patients (including family and informal caregivers) as active participants, collaborators, advisors and ...

• AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale 

  Fu, Cynthia H. Y.; Erus, Guray; Fan, Yong; Antoniades, Mathilde; Arnone, Danilo; Arnott, Stephen R.; Chen, Taolin; Choi, Ki S.; Fatt, Cherise C.; Frey, Benicio N.; Frokjaer, Vibe G.; Ganz, Melanie; Garcia, Jose; Godlewska, Beata R.; Hassel, Stefanie; Ho, Keith; McIntosh, Andrew M.; Qin, Kun; Rotzinger, Susan; Sacchet, Matthew D.; Savitz, Jonathan; Shou, Haochang; Singh, Ashish; Stolicyn, Aleks; Strigo, Irina; Strother, Stephen C.; Tosun, Duygu; Victor, Teresa A.; Wei, Dongtao; Wise, Toby; Woodham, Rachel D.; Zahn, Roland; Anderson, Ian M.; Deakin, J. F. W.; Dunlop, Boadie W.; Elliott, Rebecca; Gong, Qiyong; Gotlib, Ian H.; Harmer, Catherine J.; Kennedy, Sidney H.; Knudsen, Gitte M.; Mayberg, Helen S.; Paulus, Martin P.; Qiu, Jiang; Trivedi, Madhukar H.; Whalley, Heather C.; Yan, Chao-Gan; Young, Allan H.; Davatzikos, Christos (2023-01-23)

  Abstract Background Efforts to develop neuroimaging-based biomarkers in major depressive disorder (MDD), at the individual level, have been limited to date. As diagnostic ...

• “You need a team”: perspectives on interdisciplinary symptom management using patient-reported outcome measures in hemodialysis care—a qualitative study 

  Baragar, Brigitte; Schick-Makaroff, Kara; Manns, Braden; Love, Shannan; Donald, Maoliosa; Santana, Maria; Corradetti, Bonnie; Finlay, Juli; Johnson, Jeffrey A.; Walsh, Michael; Elliott, Meghan J. (2023-01-20)

  Abstract Background Patient-reported outcome measures (PROMs) are standardized instruments used for assessing patients’ perspectives on their health status at a point in time, ...

• Guideline LDL-C Threshold Achievement in Acute Myocardial Infarction Patients: A Real-World Evidence Study Demonstrating the Impact of Treatment Intensification with PCSK9i 

  Mackinnon, Erin S.; Har, Bryan; Champsi, Salimah; Wani, Rajvi J.; Geyer, Lee; Shaw, Eileen; Farris, Megan S.; Anderson, Todd J. (2023-01-19)

  Abstract Introduction A high proportion of Canadian patients with acute myocardial infarction (AMI) do not achieve the threshold low-density lipoprotein cholesterol (LDL-C) levels ...

• A qualitative description of barriers to visual rehabilitation experienced by stroke survivors with visual impairment in Alberta, Canada 

  Manhas, Kiran P.; Brehon, Katelyn; Jiang, Jennis; Damji, Karim F.; Costello, Fiona (2023-01-20)

  Abstract Background Post-stroke visual impairment (VI) is a common but under-recognized care challenge. Common manifestations of post-stroke VI include: diplopia, homonymous ...

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