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A multi-center, randomized, 12-month, parallel-group, feasibility study to assess the acceptability and preliminary impact of family navigation plus usual care versus usual care on attrition in managing pediatric obesity: a study protocol
(2023-01-23)Abstract Background Pediatric obesity management can be successful, but some families discontinue care prematurely (i.e., attrition), limiting treatment impact. Attrition is ... -
Parkin coregulates glutathione metabolism in adult mammalian brain
(2023-01-23)Abstract We recently discovered that the expression of PRKN, a young-onset Parkinson disease-linked gene, confers redox homeostasis. To further examine the protective effects of parkin in an oxidative stress ... -
Preoperative hemoglobin and perioperative blood transfusion in major head and neck surgery: a systematic review and meta-analysis
(2023-01-24)Abstract Background There is a growing concern with inappropriate, excessive perioperative blood transfusions. Understanding the influence of low preoperative hemoglobin (Hgb) ... -
The use of machine learning and deep learning techniques to assess proprioceptive impairments of the upper limb after stroke
(2023-01-27)Abstract Background Robots can generate rich kinematic datasets that have the potential to provide far more insight into impairments than standard clinical ordinal scales. ... -
Effect of mobile application types on stroke rehabilitation: a systematic review
(2023-01-24)Abstract Background Stroke is a significant contributor of worldwide disability and morbidity with substantial economic consequences. Rehabilitation is a vital component of ... -
Towards conceptualizing patients as partners in health systems: a systematic review and descriptive synthesis
(2023-01-25)Abstract Background With the sharp increase in the involvement of patients (including family and informal caregivers) as active participants, collaborators, advisors and ... -
AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale
(2023-01-23)Abstract Background Efforts to develop neuroimaging-based biomarkers in major depressive disorder (MDD), at the individual level, have been limited to date. As diagnostic ... -
“You need a team”: perspectives on interdisciplinary symptom management using patient-reported outcome measures in hemodialysis care—a qualitative study
(2023-01-20)Abstract Background Patient-reported outcome measures (PROMs) are standardized instruments used for assessing patients’ perspectives on their health status at a point in time, ... -
Guideline LDL-C Threshold Achievement in Acute Myocardial Infarction Patients: A Real-World Evidence Study Demonstrating the Impact of Treatment Intensification with PCSK9i
(2023-01-19)Abstract Introduction A high proportion of Canadian patients with acute myocardial infarction (AMI) do not achieve the threshold low-density lipoprotein cholesterol (LDL-C) levels ... -
A qualitative description of barriers to visual rehabilitation experienced by stroke survivors with visual impairment in Alberta, Canada
(2023-01-20)Abstract Background Post-stroke visual impairment (VI) is a common but under-recognized care challenge. Common manifestations of post-stroke VI include: diplopia, homonymous ...