• When human guanylate-binding proteins meet viral infections 

  Zhang, Rongzhao; Li, Zhixin; Tang, Yan-Dong; Su, Chenhe; Zheng, Chunfu (2021-03-05)

  Abstract Innate immunity is the first line of host defense against viral infection. After invading into the cells, pathogen-associated-molecular-patterns derived from viruses are recognized by pattern recognition ...

• When MARCH family proteins meet viral infections 

  Zheng, Chunfu; Tang, Yan-Dong (2021-03-02)

  Abstract Membrane-associated RING-CH (MARCH) ubiquitin ligases belong to a RING finger domain E3 ligases family. Recent studies have demonstrated that MARCH proteins play critical roles during various viral ...

• Ethosuximide inhibits acute histamine- and chloroquine-induced scratching behavior in mice 

  Gadotti, Vinicius M.; Zamponi, Gerald W. (2021-03-02)

  Abstract We have recently reported that the Cav3.2 T-type calcium channel which is well known for its key role in pain signalling, also mediates a critical function in the transmission of itch/pruritus. Here, ...

• Planting seeds of change: reconceptualizing what people eat as eating practices and patterns 

  Olstad, Dana L.; Kirkpatrick, Sharon I. (2021-03-04)

  Abstract Language focused on individual dietary behaviors, or alternatively, lifestyle choices or decisions, suggests that what people eat and drink is primarily a choice that comes down to free will. Referring ...

• Recurrent epiphora after dacryocystorhinostomy surgery: Structural abnormalities identified with dacryocystography and long term outcomes of revision surgery 

  Timlin, Hannah M.; Kang, Swan; Jiang, Kailun; Ezra, Daniel G. (2021-03-05)

  Abstract Background To investigate the aetiopathology of recurrent epiphora or stickiness after dacryocystorhinostomy (DCR) surgery, identifiable on dacryocystography (DCG), ...

• Multi-centre implementation of an Educational program to improve the Cardiac Arrest diagnostic accuracy of ambulance Telecommunicators and survival outcomes for sudden cardiac arrest victims: the EduCATe study design and methodology 

  Vaillancourt, Christian; Charette, Manya; Naidoo, Sarika; Taljaard, Monica; Church, Matthew; Hodges, Stephanie; Leduc, Shannon; Christenson, Jim; Cheskes, Sheldon; Dainty, Katie; Feldman, Michael; Goldstein, Judah; Tallon, John; Helmer, Jennie; Sibley, Aaron; Spidel, Matthew; Blanchard, Ian; Garland, Jim; Cyr, Kathryn; Brehaut, Jamie; Dorian, Paul; Lacroix, Colette; Zambon, Sandra; Thiruganasambandamoorthy, Venkatesh (2021-03-04)

  Abstract Background Sudden cardiac death remains a leading cause of mortality in Canada, resulting in more than 35,000 deaths annually. Most cardiac arrest victims collapse ...

• Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening 

  Bao, Bo; Liu, Crystal S.; Masson, Edward C. O.; Abele, Jonathan T. (2021-02-28)

  Abstract Purpose To evaluate the diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic prosthesis loosening following hip and knee arthroplasty. ...

• Developing a Canadian evaluation framework for patient and public engagement in research: study protocol 

  L’Espérance, Audrey; O’Brien, Nadia; Grégoire, Alexandre; Abelson, Julia; Canfield, Carolyn; Del Grande, Claudio; Dogba, Maman J.; Fancott, Carol; Levasseur, Mary A.; Loignon, Christine; Majnemer, Annette; Pomey, Marie-Pascale; Rasiah, Jananee; Salsberg, Jon; Santana, Maria; Tremblay, Marie-Claude; Urquhart, Robin; Boivin, Antoine (2021-02-25)

  Abstract Background Patient and public engagement (PPE) in research is growing internationally, and with it, the interest for its evaluation. In Canada, the Strategy for ...

• Malignancy risk of hyperfunctioning thyroid nodules compared with non-toxic nodules: systematic review and a meta-analysis 

  Lau, Lorraine W.; Ghaznavi, Sana; Frolkis, Alexandra D.; Stephenson, Alexandra; Robertson, Helen L.; Rabi, Doreen M.; Paschke, Ralf (2021-02-25)

  Abstract Background Hyperfunctioning or hot nodules are thought to be rarely malignant. As such, current guidelines recommend that hot nodules be excluded from further malignancy ...

• Trauma quality indicators: internationally approved core factors for trauma management quality evaluation 

  Coccolini, Federico; Kluger, Yoram; Moore, Ernest E.; Maier, Ronald V.; Coimbra, Raul; Ordoñez, Carlos; Ivatury, Rao; Kirkpatrick, Andrew W.; Biffl, Walter; Sartelli, Massimo; Hecker, Andreas; Ansaloni, Luca; Leppaniemi, Ari; Reva, Viktor; Civil, Ian; Vega, Felipe; Chiarugi, Massimo; Chichom-Mefire, Alain; Sakakushev, Boris; Peitzman, Andrew; Chiara, Osvaldo; Abu-Zidan, Fikri; Maegele, Marc; Miccoli, Mario; Chirica, Mircea; Khokha, Vladimir; Sugrue, Michael; Fraga, Gustavo P.; Otomo, Yasuhiro; Baiocchi, Gian L.; Catena, Fausto (2021-02-23)

  Abstract Introduction Quality in medical care must be measured in order to be improved. Trauma management is part of health care, and by definition, it must be checked constantly. ...

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