Frailty in older adults (≥50 years) living with Human Immunodeficiency Virus (HIV)

Date
2018-07-06
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Abstract
Antiretroviral therapy (ART) has increased the life expectancy of persons living with HIV/AIDS (PLWHA). Fifty percent of PLWHA are ≥ 50 years of age, and age-related comorbidities are an increasing concern. The prevalence of frailty in HIV is greater than in age-matched controls. We investigated a cohort of older (≥ 50 years) PLWHA at the Southern Alberta Clinic (SAC) in Calgary, Alberta, and screened for frailty. Patients were screened using three frailty measures: a Modified Frailty Phenotype, Clinical Frailty Scale and the Frailty Index. Patients identified as frail were offered a Comprehensive Geriatric Assessment performed by a Geriatrician and the results were shared with the HIV provider and the family physician. Over three hundred patients were screened using the MFP and CFS, and over 700 patients had a FI calculated. Frailty was associated with duration of ART, but not with known duration of HIV infection, CD4 cell count, viral load, or age.
Description
Keywords
Older adult, Frailty, Human Immunodeficiency Virus, HIV, Geriatric Medicine, Geriatrics, Aging
Citation
McMillan, J. M. (2018). Frailty in older adults (≥50 years) living with Human Immunodeficiency Virus (HIV) (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/32402