Salivary and urinary methodology for ovulation and menstrual cycle phase detection among eumenorrheic females: A scoping review protocol
Date
2022-05-03
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Abstract
Most females will experience variability in their menstrual cycle (MC) at some point across the reproductive lifespan (Bull et al., 2019). Current literature suggests that it is important for females to track MC regularity and ovulation occurrence as it is related to other health outcomes (Lynch et al., 2014). MC tracking and ovulation can be detected using a variety of methods (Allen et al., 2017). The gold standard for ovulation detection includes daily transvaginal ultrasonography and laparoscopic evaluation of the developing follicle until the point of rupture. These methods, however, can be costly, invasive, and have a large participant burden (Allen et al., 2017; Lynch et al., 2014). Therefore, accessible, and reliable methods of ovulation and MC phase detection are warranted. The study objective is to examine methods in the literature associated with salivary assay and urinary hormone testing for ovulation and menstrual cycle phase detection. Inclusion criteria for participants and defining characteristics consist of the following a) eumenorrheic females between 18 to 45 years of age, b) salivary and/or urinary hormone testing methods, c) menstrual cycle measurement, d) ovulation detection, and e) estradiol, progesterone, and/or luteinizing hormone (LH) measures. The proposed scoping review will be conducted in accordance with the JBI methodology for scoping reviews described in the JBI Manual for Evidence Synthesis (2020). The review will also cover the 2018 PRISMA reporting items for scoping review extensions (Tricco et al., 2018). Population: Eumenorrheic Females. Concept: Salivary and Urinary Hormone Testing Methods. Context: Ovulation and Menstrual Cycle Phase Detection
PRIMARY QUESTION: What is the validity and reliability of salivary and urinary assay testing for female sex hormones in ovulation detection and menstrual cycle phase identification? SECONDARY QUESTION: What are the salivary and urinary protocols used to test female sex hormones and what ranges are considered within normal? TERTIARY QUESTION: Are salivary and urinary assays for female sex hormones (estrogen, progesterone, and luteinizing hormone) comparable to the gold standard, serum, in relation to the menstrual cycle?"
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Keywords
Scoping Review, Scoping Review Protocol, Estrogen, Progesterone, Luteinizing Hormone, Menstrual Cycle, Ovulation Detection, Salivary Estrogen Testing Methods, Salivary Progesterone Testing Methods, Urinary LH Testing Methods
Citation
Doroshuk, M. L., Kazakoff, A., Hayden, K. A., & Doyle-Baker, P. K. (2022). Salivary and urinary methodology for ovulation and menstrual cycle phase detection among eumenorrheic females: A scoping review protocol. University of Calgary.
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| Version | Date | Summary |
|---|---|---|
2* | 2022-06-28 18:03:11 | The preliminary screening indicated that the inclusion criteria were too broad and not well defined. This was determined by number of eligible records for full text review that was beyond the capacity of the research team. |
| 2022-05-05 19:50:47 | Preliminary Protocol |
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