Cognitive functioning and positive and negative symptoms in schizophrenia

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The first purpose of this study was to examine the relationship of cognitive functioning and positive and negative symptoms in schizophrenia. The second purpose was to determine whether there was a differential pattern of cognitive deficits associated symptoms. The third purpose was to see if cognitive functioning, negative symptoms and premorbid functioning were interrelated. Positive and negative symptoms were assessed and a battery of different cognitive tests were given. The sample consisted of fifty acutely ill schizophrenics who were assessed within the first week of their admission to a general hospital psychiatric ward. The data was analyzed using multiple regression analyses. Results of these analyses suggest that negative symptoms and not positive symptoms were associated with cognitive impairment. Furthermore, positive and negative symptoms were not differentially associated with specific patterns of cognitive deficits. Negative symptoms were associated with both tests of verbal ability and tests of visual-motor and visual spatial ability. Secondly, there were significant intercorrelations among negative symptoms, cognitive impairments, and poor premorbid functioning. The results were interpreted in terms of the concept that cognitive difficulties experienced by psychotic patients is a transient state that may fluctuate with changes in symptoms, whereas the deficits that are associated with negative symptoms are possible traits.
Bibliography: p. 206-236.
Addington, J. J. (1987). Cognitive functioning and positive and negative symptoms in schizophrenia (Doctoral thesis, University of Calgary, Calgary, Canada). Retrieved from doi:10.11575/PRISM/13019