The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods

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Author
Kaplan, BonnieGiesbrecht, Gerald
Leung, Brenda
Field, Catherine
Dewey, Deborah
Bell, Rhonda
Manca, Donna
O'Beirne, Maeve
Johnston, David
Pop, Victor
Singhal, Nalini
Gagnon, Lisa
Bernier, Francois
Eliasziw, Misha
McCargar, Linda
Kooistra, Libbe
Farmer, Anna
Cantell, Marja
Goonewardene, Laki
Casey, Linda
Letourneau, Nicole
Martin, Jonathan
APrON Study Team
Accessioned
2015-11-07T04:14:01ZAvailable
2015-11-07T04:14:01ZIssued
2014-01Subject
Longitudinal cohort studyPregnancy
Nutrition
Mental health
Birth outcomes
Neurodevelopmental outcomes
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Abstract
The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offspring and many of their partners).The primary aims of the APrON study were to determine the relationships between maternal nutrient intake and status, before, during and after gestation, and (1) maternal mood; (2) birth and obstetric outcomes; and (3) infant neurodevelopment. We have collected comprehensive maternal nutrition, anthropometric, biological and mental health data at multiple points in the pregnancy and the post-partum period, as well as obstetrical, birth, health and neurodevelopmental outcomes of these pregnancies. The study continues to follow the infants through to 36 months of age.The current report describes the study design and methods, and findings of some pilot work. The APrON study is a significant resource with opportunities for collaboration.Refereed
YesSponsorship
This study was funded by a grant from Alberta Innovates-Health Solutions.Article deposited according to publisher policies: http://olabout.wiley.com/WileyCDA/Section/id-820227.html