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Endocarditis caused by an oral taxon species of Bergeyella identified by partial 16S rDNA sequencing: case report and review of the literature
dc.contributor.author | Clark, Lauren | |
dc.contributor.author | Parkins, Michael D | |
dc.contributor.author | Chow, Barbara L | |
dc.contributor.author | Lynch, Tarah | |
dc.contributor.author | Church, Deirdre | |
dc.date.accessioned | 2017-09-06T16:31:34Z | |
dc.date.available | 2017-09-06T16:31:34Z | |
dc.date.issued | 2017 | |
dc.identifier.uri | http://hdl.handle.net/1880/52207 | |
dc.description.abstract | Bergeyella spp bacteremia is a rare cause of infective endocarditis and is typically associated with animal contact. This case report presents a case of culture-negative endocarditis caused by Bergeyella spp oral taxon 422 in a 49-year-old man with severe periodontal disease but no animal contact. Multiple sets of blood cultures were negative, but broad-range 16S rDNA polymerase chain reaction (PCR) amplification and sequencing repeatedly detected this organism in the patient’s bloodstream. Empiric broad-spectrum antibiotic treatment against Bergeyella spp resulted in resolution of clinical symptoms, resolution of bloodstream infection, and cure. This is the first human case of endocarditis caused by an oral-associated species of Bergeyella described in the literature. Culture-negative endocarditis due to Bergeyella spp from severe periodontal disease may be missed unless molecular detection methods are used. | en_US |
dc.description.sponsorship | Open Access Authors Fund | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Toronto Press | en_US |
dc.rights | Attribution Non-Commercial 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | endocarditis | en_US |
dc.subject | Bergeyella spp | en_US |
dc.subject | periodontal disease | en_US |
dc.subject | broad-range 16S PCR | en_US |
dc.title | Endocarditis caused by an oral taxon species of Bergeyella identified by partial 16S rDNA sequencing: case report and review of the literature | en_US |
dc.type | journal article | |
dc.description.refereed | Yes | en_US |
dc.publisher.url | http://jammi.utpjournals.press/ | en_US |
dc.publisher.faculty | Cumming School of Medicine | en_US |
dc.publisher.department | Medicine | en_US |
dc.publisher.institution | University of Calgary | en_US |
dc.identifier.doi | http://dx.doi.org/10.11575/PRISM/33833 |