Physical activity (PA) and sports benefit the physical and mental well-being of children and adolescents in community samples. Children and adolescents with specific learning disorder (SLD) have a higher risk of experiencing poorer mental health than their typically developing peers. Unfortunately, very little research has investigated the role sports may play in the mental health of individuals in this population. This study compared mental health symptoms between children and adolescents with SLD who participate in sports and those who do not participate in sports to better understand how sports impact the mental health of individuals with SLD. A secondary aim was to investigate gender differences in these associations. Data were collected via an online survey where parents answered questions concerning their child’s mental health, sports involvement, daily PA, as well as other demographic and lifestyle related questions. Symptoms of depression, anxiety, inattention, and hyperactivity were measured using the Patient Health Questionnaire – 9 (PHQ-9), the seven-item Generalized Anxiety Disorder (GAD-7) scale, and the Swanson, Nolan, and Pelham Questionnaire (SNAP-IV). Results demonstrated a small effect of participation in sports on symptoms of anxiety, as well as on inattention in girls but not boys. No associations were found between sports and mental health for boys. These results indicate that sports may have some benefit for anxiety and inattention in children and adolescents with SLD; however, additional research is required due to small effect sizes and low generalizability. Overall, this study sparks the conversation of how sports could be a helpful opportunity for individuals with SLD