McLaren, LindsayBarberio, Amanda2016-10-132016-10-1320162016Barberio, A. (2016). A Canadian Population-based Study of the Relationship between Fluoride Exposure and Indicators of Cognitive and Thyroid Functioning; Implications for Community Water Fluoridation (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/24639http://hdl.handle.net/11023/3428Concerns exist regarding potential harms of community water fluoridation. The study objective was to examine the association between fluoride exposure and indicators of two health outcomes for which concerns have been expressed, cognitive and thyroid functioning, among a population-based sample of Canadians. Data were analyzed from Cycles 2 and 3 of the Canadian Health Measures Survey. Logistic regression and multinomial logistic regression were used to examine associations between fluoride exposure (from urine and tap water) and indicators of cognitive and thyroid functioning, adjusting for covariates. There was no evidence of any relationship between fluoride exposure and thyroid functioning. Higher urinary fluoride was associated with having some cognitive problems (versus none), but this finding disappeared when the sample was constrained to those for whom we could discern fluoride exposure from drinking water. Future research should continue to utilize this high quality data source to explore other potential harms.engUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.Public Healthmaster thesis10.11575/PRISM/24639