Khan, AnealRamage, BarbaraRobu, IonBenard, Laura2018-09-272018-09-272009-05-25Aneal Khan, Barbara Ramage, Ion Robu, and Laura Benard, “Side-Alternating Vibration Training Improves Muscle Performance in a Patient with Late-Onset Pompe Disease,” Case Reports in Medicine, vol. 2009, Article ID 741087, 4 pages, 2009. doi:10.1155/2009/741087http://hdl.handle.net/1880/108495https://doi.org/10.11575/PRISM/44480Side-alternating vibration training (SAVT) was used for 15 weeks in a patient with Late-onset Pompe disease who had never used enzyme replacement or chaperone therapy. Prior to the use of SAVT, the patient had experienced declining muscle performance and her 6-minute walk distance decreased from 210 to 155 metres in 6 months. After SAVT, her 6-minute walk distance increased 70% from 166 to 282 metres, muscle jumping power increased by 64% from 83 to 166 watts, isometric knee extensor strength increased 17% from 38 to 44 Nm, and she achieved a more normal pattern of ankle, knee, andjoint kinematics and kinetics. Her functional ability measured through the Rotterdam 9-item score was unchanged at 19/36. There were no elevations in serum creatine kinase or lactate. This is the first report, to our knowledge, of a performance improvement in a patient with Pompe disease using SAVT.Journal Article2018-09-27enCopyright © 2009 Aneal Khan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.https://doi.org/10.1155/2009/741087