Abughazaleh, NadaAbusara, ZiadKrawetz, Roman J.Herzog, Walter2020-06-302020-06-302020-08Abughazaleh, N., Abusara, Z., Krawetz, R., & Herzog, W. (2020). The influence of maximal and submaximal cyclic concentric and eccentric exercise on chondrocyte death and synovial fluid proteins in the rabbit knee. Clinical Biomechanics, 78 doi:10.1016/j.clinbiomech.2020.1050950268-00331879-1271http://hdl.handle.net/1880/112233https://dx.doi.org/10.11575/PRISM/37959Mechanical stimulation of joints regulates the biosynthetic activity of chondrocytes. It has been argued that excessive loading might cause chondrocyte death, leading to degeneration of cartilage and cause osteoarthritis. The aims of this study were to apply a high, short-term loading, and a low intensity, long-term loading protocol to intact joints in life animals and determine changes in synovial fluid and the percentage of dead cells in rabbit knee cartilageengUnless otherwise indicated, this material is protected by copyright and has been made available with authorization from the copyright owner. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.Muscular loadingSynovial fluidProtein contentChondrocytesCell viabilityjournal article201201854, FDN-14334110.1016/j.clinbiomech.2020.105095