Clement, FionaKim, Jong2017-04-132017-04-1320172017Kim, J. (2017). Economic Evaluation of a Human Papillomavirus Vaccination Program for Grade 5 Boys in Alberta (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25783http://hdl.handle.net/11023/3698Vaccination prevents Human papillomavirus (HPV) associated diseases. This study is a cost-utility analysis about adding boys to the HPV immunization program for girls in an Albertan and Canadian context, using a decision tree based model. Individuals in Grade 5 can be a boy or girl, and vaccinated or not vaccinated. Then, they can get a disease; and either survive or die. Included diseases were cervical, anal, head and neck, vaginal, vulvar, penile cancers, and anogenital warts. Parameters were adjusted to 2016 Canadian dollar and discounted 5% annually. The incremental cost effectiveness ratio (ICER) per quality adjusted life years for adding boys to the girls-only vaccination is $333,420. In sensitivity analysis, discount rate and herd immunity had the largest impact. Given the female coverage rate in Alberta, additional vaccination of boys would not be cost-effective because herd immunity reduces benefits. Policy justification of adding boys should expand beyond cost-effectiveness.engUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.Public HealthHuman PapillomavirusVaccinationEconomic Evaluationmaster thesis10.11575/PRISM/25783