Enriquez Garcia, AlejandraLai, BarryGopinathan, Sesha GopalHarris, Hugh H.Shemanko, Carrie S.Jalilehvand, Farideh2021-07-302019-06-05Enriquez Garcia, A., Lai, B., Gopinathan, S. G., Harris, H. H., Shemanko, C. S., & Jalilehvand, F. (2019). Nuclear localization of dirhodium(II) complexes in breast cancer cells by X-ray fluorescence microscopy. Chemical Communications, 55(57), 8223–8226. doi:10.1039/c9cc00521h1359-7345http://hdl.handle.net/1880/113674https://dx.doi.org/10.11575/PRISM/39045The cellular distribution of three dirhodium(II) complexes with a paddlewheel structure was investigated using synchrotron-based X-ray fluorescence microscopy and cell viability studies. Complexes with vacant axial sites displayed cytotoxic activity and nuclear accumulation whereas complexes in which the axial positions were blocked showed little to no toxicity nor uptake.enUnless otherwise indicated, this material is protected by copyright and has been made available with authorization from the copyright owner. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.journal articleRGPIN 2016-04546RGPIN-2018-04773#30007210.1039/C9CC00521H