Menon, Bijoy K.Batchelor, Connor2016-10-112016-10-1120162016Batchelor, C. (2016). Predicting the Risk of Intracerebral Haemorrhage in Patients with Acute Ischemic Stroke Receiving IV-alteplase with or Without Endovascular Thrombectomy (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/27406http://hdl.handle.net/11023/3416Intracerebral Haemorrhage (ICH) is a devastating complication of acute ischemic stroke (AIS) treatment with no known effective management protocols. The need to identify patients at risk of developing this condition is becoming increasingly recognized among the stroke community. Computed tomography perfusion (CTP) is a powerful diagnostic imaging tool that measures blood flow in the brain. This tool can also be used to provide information regarding the integrity of the blood-brain barrier (BBB). Severe brain ischemia and consequent disruption of the BBB are probable mechanisms for why ICH occurs after AIS treatment. The goal of my research is to investigate the potential role of CTP primarily and other imaging and clinical parameters in predicting ICH secondary to AIS treatment in patients.engUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.NeuroscienceAcute Ischemic StrokeCT PerfusionIntracerebral HemorrhageTissue Plasminogen ActivatorStrokeBlood-brain Barriermaster thesis10.11575/PRISM/27406