Stadel, Jessica T.Back, Thomas George2024-01-112024-01-112024Stadel, J. T., & Back, T. G. (2024). Asymmetric Synthesis with Organoselenium Compounds – The Past Twelve Years. Chemistry – A European Journal. https://doi.org/10.1002/chem.2023040740947-6539https://hdl.handle.net/1880/117934https://doi.org/10.11575/PRISM/42777The discovery and synthetic applications of novel organoselenium compounds and their reactions proceeded rapidly during the past fifty years and such processes are now carried out routinely in many laboratories. At the same time, the growing demand for new enantioselective processes provided new challenges. The convergence of selenium chemistry and asymmetric synthesis led to key developments in the 1970s, although the majority of early work was based on stoichiometric processes. More recently, greater emphasis has been placed on greener catalytic variations, along with the discovery of novel reactions and a deeper understanding of their mechanisms. The present review covers the literature in this field from 2010 to early 2023 and encompasses asymmetric reactions mediated by chiral selenium‐based reagents, auxiliaries and, especially, catalysts. Protocols based on achiral selenium compounds in conjunction with other species of chiral catalysts, as well as reactions that are controlled by chiral substrates, are also included.enUnless otherwise indicated, this material is protected by copyright and has been made available with authorization from the copyright owner. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.SeleniumAsymmetric synthesisAsymmetric catalysisStereochemistrySynthetic methodsArticlehttps://doi.org/10.1002/chem.202304074