Jetté, NathalieMcChesney, Jane2012-12-122013-06-152012-12-122012McChesney, J. (2012). Development and Validation of an ICD-10 Case Definition for Pediatric Traumatic Brain Injury using Canadian Administrative Data (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25648http://hdl.handle.net/11023/345Background: Administrative data are used for disease surveillance and research. A validated case definition to study pediatric traumatic brain injury(TBI)using administrative data is not available. Methods: Using systematic review methodology, we identified studies validating TBI ICD coding. Second, a cohort of children with and without TBI from a pediatric emergency department (ER) was linked to administrative hospital and emergency databases. Nine ICD-10 based algorithms were tested. Sensitivity, specificity, and positive/negative predictive value (PPV, NPV) were calculated. Results: We identified three studies from the systematic review with varying diagnostic accuracy, and none were pediatric specific. The best algorithm to identify TBI cases was, “1 Hospital or 1 ER visit in 1 year”: sensitivity 69.8%, (67.3-72.2), specificity 96.7% (96.2-97.2), PPV 84.2% (82.0-86.3), NPV 92.7% (92.0-93.3). Conclusion: This study algorithm is best to capture ER or hospitalized TBI cases. Future research should develop algorithms which include children seen in the community.engUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.Health SciencesHealth Services ResearchSurveillanceCoding AlgorithmsTraumatic Brain InjuryAdministrative Datamaster thesis10.11575/PRISM/25648