MacRae, JenniferQuinn, RobertLeung, Kelvin Cheuk-Wai2017-01-022017-01-0220162016Leung, K. C. (2016). Blood Volume Monitoring Guided Ultrafiltration Biofeedback on the Reduction of Intradialytic Hypotensive Episodes in Hemodialysis (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25151http://hdl.handle.net/11023/3531The majority of patients with end stage renal disease rely on hemodialysis (HD) to maintain fluid balance. Unfortunately, rapid fluid removal [ultrafiltration (UF)] often results in symptomatic, intradialytic hypotension (IDH). Our objective was to perform a randomized controlled crossover trial to evaluate the effectiveness of a blood volume monitoring guided UF biofeedback in the reduction of symptomatic IDH. Over the study period, symptomatic patients first had their dialysis prescription and dry weight optimized over a four-week period before being randomized to an eight-week biofeedback intervention or standard control HD. There was a two-week washout period before patients crossed over for a second eight-week study period. There were no differences in the rate of symptomatic IDH, volume status (as measured by electrical bioimpedance), or biomarkers of cardiac stress between the two groups.engUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.Medicine and SurgeryHemodialysisrandomized controlled trialBiofeedbackIntradialytic Hypotensionmaster thesis10.11575/PRISM/25151