MacKenzie-Feder, JessicaSirrs, SandraAnderson, DonaldSharif, JibranKhan, Aneal2018-09-272018-09-272011-06-02Jessica MacKenzie-Feder, Sandra Sirrs, Donald Anderson, Jibran Sharif, and Aneal Khan, “Primary Hyperparathyroidism: An Overview,” International Journal of Endocrinology, vol. 2011, Article ID 251410, 8 pages, 2011. doi:10.1155/2011/251410http://hdl.handle.net/1880/108428https://doi.org/10.11575/PRISM/45861Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.Journal Article2018-09-27enCopyright © 2011 Jessica MacKenzie-Feder et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.https://doi.org/10.1155/2011/251410