Manns, BradenHilsden, RobertHeitman, Steven James2017-12-182017-12-182012Heitman, S. J. (2012). Economic evaluation of colerectal cancer screening for average risk individuals (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/5063http://hdl.handle.net/1880/106064Bibliography: p. 58-65Includes copy of ethics approval and copyright permissions. Original copies with original Partial Copyright Licence.Background: Colorectal cancer (CRC) is a common deadly cancer. Screening for CRC saves lives and is cost-effective, but it is unclear if one or more of the screening options are preferred. Methods: A Markov model was developed and validated and then used to conduct an economic evaluation of CRC screening for average risk individuals. All current CRC screening modalities and up to date CRC treatment costs were considered. A systematic review and meta-analysis of CRC and adenomatous polyp prevalence was also performed to inform the model. Results: The prevalence of non-advanced adenomas, advanced adenomas and CRC in 50-64 and 65-75 year olds was 17.1%, 3.8% and 0.1% and 17.3%, 8.2% and 0.7%, respectively. In the base case analysis CRC screening with annual FIT reduced the risk of CRC and CRC-related deaths and was associated with lower health care costs compared to no screening and the other screening options. Conclusion: Health policy decision makers should prioritize funding for CRC screening using FIT.xi, 65 leaves : ill. ; 30 cm.engUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.master thesis10.11575/PRISM/5063