Browsing by Author "Browder, Leon W."
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- ItemOpen AccessA Novel regulator of translation during early development of xenopus laevis(1991) Fu, Loning; Browder, Leon W.
- ItemEmbargoAnalysis of transcription in lampbrush stage Rana pipiens oocytes during vitro culture(1975) Rogers, Robert Eric; Browder, Leon W.
- ItemOpen AccessChanges in the heat shock response and HSP70 and constitutive gene transcription during erythropoiesis of Xenopus laevis(1986) Winning, Robert S.; Browder, Leon W.
- ItemOpen AccessEffects of cycklin A2 non-coding regions on reporter gene translation during early development in xenopus laevis(1997) Strugnell, Tod; Browder, Leon W.
- ItemOpen AccessThe effects of Heat Shock on th Morphology and Protein Synthesis of the Epidermis of Xenopus laevis Larvae(Rockefeller University Press, 1988-03) Cavey, Michael J.; Nickells, Robert W.; Browder, Leon W.; Biological Sciences; Faculty of Science; University of CalgaryBy scanning electron microscopy, we have observed that a 20-min heat shock at 37 degrees C, although not lethal, causes extensive damage to the epidermis of 30-h and 2-d (post-fertilization) Xenopus laevis larvae. The primary effects of heat shock are the apical swelling of the epidermal cells, giving the epidermis a "cobblestone" appearance, and the selective shedding of the ciliated cells. The shed cells may be cell fragments, however, because some of them are anucleate. Shed cells also exhibit the enriched synthesis of a group of heat shock proteins of 62,000 D molecular weight, suggesting that these proteins are specific to the shed cells. Prolonged heat shock of these larvae (i.e., 30 min at 37 degrees C) results in the complete disintegration of the epidermis, followed by larval death. At later stages of development (3- d and 4-d post-fertilization), the epidermis becomes more resistant to heat-induced damage inflicted by a 20-min heat shock. This increase in resistance coincides with the development of large secretory cells and the loss of ciliated cells in the epidermis and thus parallels a change in the state of histological differentiation.
- ItemOpen AccessPost-transcriptional regulation by non-coding sequences of the c-myc transcript in the xenopus laevis(1997) Fraser, Sherri D.; Browder, Leon W.
- ItemOpen AccessStress-induced synthesis of pyruvate kinase in xenopus laevis embryos(1989) Marsden, Mungo; Browder, Leon W.
- ItemOpen AccessThe Developmental acquisition and mechanism of thermotolerance in Xenopus laevis embryos(1987) Nickells, Robert W.; Browder, Leon W.
- ItemMetadata onlyXanthine dehydrogenase in Drosophila melanogaster: a system for the study of developmental regulation(1972) Sayles, Cyril D.; Browder, Leon W.
- ItemOpen AccessXanthine dehydrogenase in Drosophila melanogaster: role of the cinnamon+ gene and the time of activation of the rosy+ gene in development(1977) Robinson, Joseph Christopher; Browder, Leon W.