Browsing by Author "Chen, Andrew"
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Item Open Access Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors(Wiley-Liss, Inc., 2009-02) Ouardouz, Mohamed; Basak, Ajoy; Chen, Andrew; Rehak, Renata; Yin, Xinghua; Coderre, Elaine M.; Zamponi, Gerald W.; Hameed, Shahid; Trapp, Bruce D. T.; Stys, Peter K.The deleterious effects of glutamate excitotoxicity are well described for central nervous system gray matter. Although overactivation of glutamate receptors also contributes to axonal injury, the mechanisms are poorly understood. Our goal was to elucidate the mechanisms of kainate receptor-dependent axonal Ca(2+) deregulation.