Browsing by Author "De Koninck, Paul"

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    Activity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase IIα
    (PLOS one, 2012-07-18) Bernier, Nikolas; De Koninck, Paul; Flynn, Robyn E.; Labrie-Dion, Étienne; Colicos, Michael A.; Zamponi, Gerald W.
    Rem2 is a small monomeric GTP-binding protein of the RGK family, whose known functions are modulation of calcium channel currents and alterations of cytoskeletal architecture. Rem2 is the only RGK protein found predominantly in the brain, where it has been linked to synaptic development. We wished to determine the effect of neuronal activity on the subcellular distribution of Rem2 and its interacting partners.