Browsing by Author "Hews-Girard, Julia"

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    Examining the impact of missing data in an undergraduate mental health survey
    (2023-08-04) Hews-Girard, Julia; Patten, Scott; Dimitropoulos, Gina; Szeto, Andrew; Thannhauser, Jennifer; Duffy, Anne; Rivera, Daniel; King, Nathan
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    Exploring Perceptions, Experiences, Acceptability and Validity of Mental Health Screening and Diagnosis among Undergraduate Students: A mixed methods study
    (2023-08-04) Hews-Girard, Julia; Patten, Scott; Dimitropoulos, Gina; Szeto, Andrew; Thannhauser, Jennifer
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    ItemOpen Access
    Psychosocial burden of type 1 and 2 hereditary angioedema: a single-center Canadian cohort study
    (2021-06-29) Hews-Girard, Julia; Goodyear, Marilyn D.
    Abstract Background Hereditary angioedema (HAE) is a rare but serious disorder associated with a multifaceted burden of illness including a high prevalence of psychiatric symptoms and impaired health-related quality of life (HRQoL). Despite recent efforts to clarify the psychosocial implications of HAE, important gaps still remain. The aim of this study was to characterize the psychosocial burden associated with HAE types 1 and 2. Methods Type 1 or 2 HAE patients (n  =  17), aged 19 years or older, completed the Depression, Anxiety, Stress Scale (DASS-21) and the DSM-5 cross cutting measures to identify psychiatric symptomatology, Angioedema Quality of Life Questionnaire (AE-QoL) and the Short-Form 36-Item Health Survey version 2 (SF-36v2) to assess disease-related and generic HRQoL respectively, and the Work Productivity and Activity Impairment Questionnaire (WPAI) to measure impact on work productivity and daily activities. Data analyses were conducted using SPSS statistical software (Version 25.0; IBM, Armonk, NY). Descriptive statistics were used to summarize continuous demographics and clinical characteristics and outcomes of interest while frequency distributions were used for categorical variables. T tests were used to compare SF-36v2 domain scores to Canadian norms and sex differences in scale scores. Results Depression [DASS-21 score  =  6.8  ±  10.2; n  =  12 (71%)] anxiety [DASS-21 score  =  6.2  ±  8.2; n  =  13 (76%)] and stress [DASS-21 score  =  10  ±  10.2; n  =  13 (76%)] were prevalent. Other psychiatric symptoms warranting inquiry included mania (n  =  14, 82.4%), anger (n  =  14, 82.4%), sleep disturbances (n  =  13, 76.5%), somatic symptoms (n  =  11, 64.7%) and impaired personality functioning (n  =  9, 52.9%). Mean AE-QoL score was 39  ±  18.2. Mean SF-36v2 domain scores were significantly lower than Canadian normative data for the entire sample (p  <  0.05). Impairment in work productivity was minimal; mean activity impairment was 20.6%  ±  21.1% [n  =  11 (64.7%)]. Female participants reported significantly greater HAE-related stress [DASS; t(15)  =   − 2.2, p  =  0.04], greater HAE-related fears [AEQoL; t(5.6)  =   − 2.7, p  =  0.04), and lower SF-36v2 domain scores than male patients. Conclusions Study findings offer specific, valuable insight into the psychosocial burden of HAE with the potential to improve clinical management of HAE. Best practices for effective management of HAE should include providing holistic care to address the psychosocial and mental health of HAE patients.
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    Validating the Brief Resilience Scale (BRS) in Undergraduate Students: A mixed methods study
    (2023-08-04) Hews-Girard, Julia; Patten, Scott; Dimitropoulos, Gina; Szeto, Andrew; Thannhauser, Jennifer; King, Nathan; Duffy, Anne; Cunningham, Simone