Browsing by Author "Leung, Alexander K.C."
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- ItemOpen AccessBe Careful, Mom and Doc: Hepatotoxicity Associated with Prescribed Medications in Young Infants(Hindawi Publishing Corporation, 2009-02-27) Hon, Kam-Lun Ellis; Leung, Alexander K.C.
- ItemOpen AccessChlamydial pneumonia: a creepy neonatal disease(Hindawi Publishing Corporation, 2013-01-16) Hon, Kam Lun; Leung, Alexander K.C.We present a case of neonatal chlamydial pneumonitis to illustrate that a high index of suspicion is necessary to make the diagnosis so that treatment can be promptly instituted. The child was afebrile and the only symptom was a cough. The respiratory equations are calculated to understand the respiratory physiology. There was no overt abnormality with ventilation, oxygenation, compliance, resistance, or ventilation-perfusion mismatch despite radiographic abnormality. The literature is searched to review if treatment with a systemic macrolide antibiotic is needed in an otherwise asymptomatic neonate with chlamydial pneumonitis.
- ItemOpen AccessComplications of bezoar in children: What is new?(Hindawi Publishing Corporation, 2013-09-11) Hon, Kam Lun; Cheng, Jean; Chow, Chung Mo; Cheung, Hon Ming; Cheung, Kam Lau; Tam, Yuk Him; Leung, Alexander K.C.A bezoar is a mass found trapped in the gastrointestinal system. The condition may be associated with pica, especially in developmentally retarded children. Clinical manifestations are usually nonspecific. Endoscopic diagnosis and removal of the foreign materials is often indicated. Occasionally, severe complications may occur. We report two cases to illustrate the clinical features and complications in these children. In the first case, a reliable history was not obtained in the developmentally delayed girl which precluded prompt diagnosis, but the grossly dilated stomach on plain abdominal radiograph gave clues to an underlying insidious mechanical obstruction of upper gastrointestinal tract. In the second case of a normal child, the unrelenting symptoms and weight loss prompt further investigations which revealed the diagnosis. Literature on pediatric bezoar is reviewed. Oesophagoduodenoscopy is the investigation of choice for diagnostic confirmation, but surgical facilities must be available to deal with acute complications.
- ItemOpen AccessDyshidrotic eczema(Enliven Archive, 2014-09-16) Leung, Alexander K.C.; Barankin, Benjamin; Hon, Kam LunDyshidrotic eczema, also known as dyshidrotic dermatitis or pompholyx, is characterized by pruritic, tense, deep-seated vesicles mainly on the palms and lateral surfaces of the fingers. In the chronic phase, scaling, desquamation, fissuring, and, sometimes, lichenification may be seen. The peak age of onset is between 20 and 30 years of age. The sex incidence is approximately equal. Most cases are idiopathic. Predisposing factors include atopy, contact allergens, contact irritants, dermatophyte infection, allergy to ingested metal, hyperhidrosis, prolonged use of protective gloves, intravenous immunoglobulin, psychological stress, and smoking. Although the disease is benign, it tends to run a chronic and relapsing course. Successful treatment requires a systemic multipronged approach that consists of avoidance of triggering factors, optimal skin care, pharmacotherapy during acute exacerbations, and education of patients/caregivers. Ultrapotent topical corticosteroids are the mainstay of pharmacotherapy.
- ItemOpen AccessGeneralized lichen nitidus in identical twins(Hindawi Publishing Corporation, 2012-10-31) Leung, Alexander K.C.; Ng, JeffreyLichen nitidus is an uncommon idiopathic chronic dermatosis characterized by minute, flesh-colored or hypopigmented, shiny papules commonly occurring on the abdomen, chest, genitalia, and extremities. The disorder is most often localized but, rarely, can become extensive or generalized. The occurrence of lichen nitidus during infancy is extremely rare. A perusal of the English literature revealed but two cases. We report two identical twins with lesions of generalized lichen nitidus noted at two months of age. The familial occurrence of lichen nitidus suggests that a genetic factor may be operative.
- ItemOpen AccessLocalized Acquired Hypertrichosis Associated with the Application of a Splint(Hindawi Publishing Corporation, 2012-01-27) Leung, Alexander K.C.; Wong, Andrew S.
- ItemOpen AccessNew Concepts in Median Nail Dystrophy, Onychomycosis, and Hand, Foot, and Mouth Disease Nail Pathology(Hindawi Publishing Corporation, 2011-12-04) Hoy, Nathan Y.; Leung, Alexander K.C.; Metelitsa, Andrei I.; Adams, Stewart
- ItemOpen AccessPersistent salmon patch on the forehead and glabellum in a Chinese adult(Hindawi Publishing Corporation, 2014-05-14) Leung, Alexander K.C.Salmon patches are present in approximately 44% of all neonates. The lesions tend to fade with time and those on the glabellum, eyelids, nose, and upper lip are rarely detected after the age of 6. We report a 33-year-old Chinese female with a salmon patch on the forehead and glabellum. To our knowledge, the occurrence of a salmon patch on the forehead and glabellum in adulthood has not been reported. The persistent salmon patch on the face of an adult is benign and not associated with any neurocutaneous syndrome or underlying vascular abnormality. The color of the lesion can be ameliorated with laser therapy if cosmesis is a concern.
- ItemOpen AccessPhysiological striae atrophicae of adolescence with involvement of the upper back(Hindawi Publishing Corporation, 2013-07-07) Leung, Alexander K.C.We report a 13-year-old boy with multiple purplish, atrophic, horizontal linear striae in the thoracic area. He reported a growth spurt in the preceding 12 months. His past health was unremarkable, and he took no medications. To our knowledge, physiological striae atrophicae of adolescence where idiopathic striae were restricted to the upper back have rarely been reported. Physiological striae atrophicae of adolescence may, on occasions, be mistaken for child abuse. It is important that child care professionals recognize this condition so that false accusations of child abuse will not be made.
- ItemOpen AccessSepticemia in a neonate following therapeutic hypothermia: the literature review of evidence(Hindawi Publishing Corporation, 2013-07-31) Hon, Kam Lun; Li, Joshua J.X.; Cheng, Bernadette L.Y.; Leung, Alexander K.C.We report a term neonate with hypoxic ischemic encephalopathy who underwent a 72-hour therapeutic hypothermia. He developed unstable body temperature associated with coagulase negative staphylococcus septicemia 2 weeks later which was promptly treated with intravenous antibiotics and made a good recovery. PubMed (a service of the U.S. National Library of Medicine) was searched for the terms “therapeutic hypothermia” and “septicemia,” with limits activated (humans, English, age 0–18 years). There were only 6 randomized controlled trials, 1 non-randomized controlled trial, 1 retrospective cohort, and 1 case-control trial, which showed no definite evidence of increased risk of septicemia or neutrophil dysfunction in infants following hypothermia therapy.