Browsing by Author "Sauve, Reginald"
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Item Open Access Coagulase-negative Staphylococcus Sepsis in Preterm Infants and Long Term Neurodevelopmental Outcome(2013-05-27) Alshaikh, Belal; Sauve, ReginaldObjective: To examine the effect of Coagulase-negative Staphylococcus (CoNS) sepsis in preterm infants on the neonatal and neurodevelopmental outcomes at 36 months corrected age (CA). Design: A retrospective cohort study. Subjects: All preterm infants with gestational age ≤ 28 weeks. Results: A total of 105 eligible infants were exposed to CoNS sepsis between 1995 and 2008. Infants exposed to CoNS sepsis were less mature (25.9 ± 1.7 vs. 26.2 ± 1.4, p=0.04), had increased risk of retinopathy of prematurity (ROP) (adjusted RR 1.32; 95% CI 1.11 – 1.54), and were more likely to stay longer in the neonatal intensive care unit. Multivariable logistic regression analysis revealed CoNS sepsis is an independent predictor for cognitive delay (adjusted RR 1.98; 95% CI 1.01 – 3.63). Conclusions: CoNS sepsis in preterm infants is associated with increased risk for ROP in the neonatal period and for cognitive delay at 36 months CA.Item Open Access Estimation of Cumulative Incidence in the Presence of Competing Risks: Application to Clinical Oncology(2008) Brar, Satwant Sony; Sauve, Reginald; Brasher, PenelopeItem Open Access The role of feeding practices in the relationship between postpartum depression and child growth: Analysis of the All Our Babies study(2017-12-20) Lee, Yoon Shin; Fenton, Tanis; Sauve, Reginald; Rose, Marianne; McDonald, Sheila; Benzies, KarenThe purpose of this study was to examine the relationships among postpartum depression at 4 months of age, feeding practices and child growth at age 2 years. This study used data from 1881 mothers participating in the All Our Babies Study in Calgary. The mothers participated in five surveys between 24 weeks gestation and 2 years of child age. Multivariable regression analysis was done. Postpartum depression was negatively related to exclusive breastfeeding duration (β = -2.30 weeks, 95% CI: -4.39, -0.22). Postpartum depression and feeding practices were unrelated to child growth at age 2 years. We found mothers with postpartum depression at 4 months terminated exclusive breastfeeding earlier (2.3 weeks) than mothers without postpartum depression whose average exclusive breastfeeding duration was 20.2 weeks. The findings suggest a need for breastfeeding support for mothers with postpartum depression to sustain breastfeeding to the recommended duration.