The current study investigated the relationship between anxiety and social skills in high intelligent (HI) children with Attention-Deficit/Hyperactivity Disorder (ADHD) aged 8 to 11 years old. Fifteen HI children with ADHD (twice-exceptional) were matched one-to-one on age to children with HI (FSIQ ≥ 120), those with ADHD-C (average intelligence), and typically-developing children. Overall, results indicated no significant differences between self-reported anxiety and social skills; however, ADHD parent-reports of anxiety were significantly higher than typical parent-reports of anxiety. Twice-exceptional self-reports and HI self-reports were significantly lower than their parent’s reports of anxiety. For social skill abilities, twice-exceptional self-reports were significantly higher than their parents’ reports. It was also determined that anxiety was a significant predictor of twice-exceptional children’s social skills. Results of this study suggest that additional research should focus on HI as a possible risk factor for the development of anxiety and poor social skills in children with ADHD.