EUKARYO: An Agent-Based, Interactive, Virtual Reality Simulation of a Eukaryotic Cell
AuthorYuen, Douglas Wing-Kwok
Committee MemberDenzinger, Jörg
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AbstractGame engines provide sophisticated tools for rendering virtual environments. Their capabilities make them suitable for constructing detailed virtual environments. In this thesis, we present Eukaryo, an interactive, 3D model of a eukaryotic cell that was implemented in Unity and Unreal Engine. Eukaryo utilises mathematical modelling towards modelling enzyme kinetics, and agent-based modelling to illustrate the interaction between the individual proteins in the cell. Using hybrid modelling, Eukaryo is able to model the interactions for a diverse range of biological processes, such as protein activation pathways and cytoskeleton self-assembly. Further to this, Eukaryo provides support for virtual reality devices, such as the CAVE and Oculus Rift headset; users can immerse themselves in a virtual biomolecular environment. By combining state-of-the-art biological simulations with the 3D visualisations and real-time interactivity, Eukaryo provides an innovative environment for exploring cellular processes to convey the complexity in systems that constitute the machinery of life.
CitationYuen, D. W. (2016). EUKARYO: An Agent-Based, Interactive, Virtual Reality Simulation of a Eukaryotic Cell (Unpublished master's thesis). University of Calgary, Calgary, AB. doi:10.11575/PRISM/25962
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