• Information Technology
  • Human Resources
  • Careers
  • Giving
  • Library
  • Bookstore
  • Active Living
  • Continuing Education
  • Go Dinos
  • UCalgary Maps
  • UCalgary Directory
  • Academic Calendar
My UCalgary
Webmail
D2L
ARCHIBUS
IRISS
  • Faculty of Arts
  • Cumming School of Medicine
  • Faculty of Environmental Design
  • Faculty of Graduate Studies
  • Haskayne School of Business
  • Faculty of Kinesiology
  • Faculty of Law
  • Faculty of Nursing
  • Faculty of Nursing (Qatar)
  • Schulich School of Engineering
  • Faculty of Science
  • Faculty of Social Work
  • Faculty of Veterinary Medicine
  • Werklund School of Education
  • Information TechnologiesIT
  • Human ResourcesHR
  • Careers
  • Giving
  • Library
  • Bookstore
  • Active Living
  • Continuing Education
  • Go Dinos
  • UCalgary Maps
  • UCalgary Directory
  • Academic Calendar
  • Libraries and Cultural Resources
View Item 
  •   PRISM Home
  • Graduate Studies
  • The Vault: Electronic Theses and Dissertations
  • View Item
  •   PRISM Home
  • Graduate Studies
  • The Vault: Electronic Theses and Dissertations
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

β-cyclodextrins modified with different chain lengths and their physical characterization with and without the attachment to gold nanoparticles.

Download
Thesis (8.278Mb) Embargoed until: 2019-09-27
Advisor
Heyne, Belinda
Ling, Chang-Chun
Author
Lam, Wing Man
Committee Member
Cramb, David
Derksen, Darren
Anikovskiy, Max
Other
Cyclodextrin
Nile Red
Fluorescence
Gold
Nanoparticle
Subject
Chemistry
Chemistry--Organic
Chemistry--Physical
Type
Thesis
Metadata
Show full item record

Abstract
Beta-cyclodextrins (β-CDs) are a family of water soluble, naturally occurring cyclic oligosaccharides with a hydrophobic cavity that is used to host hydrophobic guest molecules. The numerous hydroxyl groups allow the native β-CD to be easily functionalized via synthetic modifications. By attaching modified CDs to the surface of gold nanoparticles (AuNPs) through a thiol moiety, its surface plasmon resonance effect can be taken advantage of. The AuNPs exhibit a photothermal effect upon irradiation which can alter the binding constant of guest molecules in β-CD hosts. Therefore, we attached novel β-CDs with different length ethylene glycol chains in hopes of studying in a distance-dependent manner the changes in the binding between the host and guest molecules. Prior to the attachment of the modified β-CDs to the surface of the AuNPs, Nile Red (NR) was utilized as a fluorescent guest to physically characterize the modified β-CDs.
Corporate
University of Calgary
Faculty
Graduate Studies
Doi
http://dx.doi.org/10.11575/PRISM/28734
Uri
http://hdl.handle.net/11023/4224
Collections
  • The Vault: Electronic Theses and Dissertations

Browse

All of PRISMCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

Most Popular ItemsStatistics by CountryMost Popular Authors

  • Email
  • SMS
  • 403.220.8895
  • Live Chat

Energize: The Campaign for Eyes High

Privacy Policy
Website feedback

University of Calgary
2500 University Drive NW
Calgary, AB T2N 1N4
CANADA

Copyright © 2017