The following thesis is an analysis on the relation between knowledge and reasoning about how to act. It seems fairly intuitive that one is rational to act on what one knows. But unfortunately, the issue is not so simple. In constructing a normative framework for practical reason, one could either require knowledge to be a necessary requirement for practical reason or one might only hold that knowledge is sufficient for reasoning about what to do, though having knowledge is not a necessary requirement. In this thesis, I will defend the latter.