Tools for Focused Ultrasound Treatment Planning
Date
2019-09-27
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Abstract
Focused Ultrasound is earning fast clinical acceptance as a treatment approach that allows sending acoustic energy into the body noninvasively. This energy is concentrated into a small focal point and depending on the wave’s intensity, frequency, and media characteristics, necrosis of the tissue can be achieved. Therefore, planning the location of the desired target is a crucial step in the therapeutic process. This thesis focused on the treatment planning of two Focused Ultrasound (FUS) systems designed for new pre-clinical and clinical applications where a user-centred approach for design was applied. The user input from researchers with a health sciences background was used to design the first system, a FUS device that works in parallel with the Sofie Biosciences uPET scan that combines both anatomical and functional imaging modalities. Second, a study on targeting feasibility was performed in patients previously diagnosed with osteomyelitis using an existing Magnetic Resonance-guided Focused Ultrasound system. The Python-based script software that allowed virtual treatment planning was also evaluated against the metrics of the user-centred design.
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Focused Ultrasound, MRgFUS, User centred design, Osteomyelitis
Citation
Viana Beserra, A. A. (2019). Tools for Focused Ultrasound Treatment Planning (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca.