Evaluation of core temperature measurement and treatment of capture-related hyperthermia in anesthetized brown bears (Ursus arctos)

Ozeki, Larissa Mourad

Evaluation of core temperature measurement and treatment of capture-related hyperthermia in anesthetized brown bears (Ursus arctos)

atmire.migration.oldid	784
dc.contributor.advisor	Caulkett, Nigel
dc.contributor.advisor	Fahlman, Åsa
dc.contributor.author	Ozeki, Larissa Mourad
dc.date.accessioned	2013-04-04T15:38:52Z
dc.date.available	2013-06-15T07:01:51Z
dc.date.issued	2013-04-04
dc.date.submitted	2013	en
dc.description.abstract	The objectives of the present study were to: 1) compare body temperature of anesthetized brown bears obtained by Vital Sense® capsules (VS) inserted gastrically to those obtained by deep rectal VS and handheld digital thermometer (HDT) and 2) to evaluate the decrease in core body temperature produced by an active cooling protocol and by alpha-2 antagonism. Thirty-one brown bears were captured with a combination of zolazepam-tiletamine and xylazine or medetomidine. One VS capsule was inserted deep into the animals’ rectum and another into the stomach. Rectal temperature was also measured with the HDT and paired data points were analyzed with the Bland-Altman technique and regression analysis. In bears that demonstrated gastric temperatures ≥ 40oC a described active cooling protocol was performed and the temperature change was analyzed for 30 minutes. To determine if antagonism of the alpha-2 agonist decreased core body temperature in bears, change in temperature was analyzed for 30 minutes after the administration of IM atipamezole. A third group of bears were not cooled and temperatures were recorded for 30 minutes before administration of atipamezole. To compare the differences among the three groups an area under the curve was calculated for each individual bear and analyzed one-way analysis of variance with Tukey’s PostHoc test. To evaluate the change over time within each treatment a General Linea Model for repeated measures was performed, with Tukey’s PostHoc test. The significance level of all analyses was 5%. VS capsules accurately measured core temperature and HDT did not accurately estimate core temperature in anesthetized brown bears. The active cooling protocol used significantly decreased body temperature of hyperthermic bears after 10 minutes. Alpha-2 antagonist produced an earlier significant decrease but the final change in temperature (at Time 30) was lower than with active cooling. No significant difference was found between the two treatments.	en_US
dc.identifier.citation	Ozeki, L. M. (2013). Evaluation of core temperature measurement and treatment of capture-related hyperthermia in anesthetized brown bears (Ursus arctos) (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25984	en_US
dc.identifier.doi	http://dx.doi.org/10.11575/PRISM/25984
dc.identifier.uri	http://hdl.handle.net/11023/585
dc.language.iso	eng
dc.publisher.faculty	Graduate Studies
dc.publisher.faculty	Veterinary Medicine
dc.publisher.institution	University of Calgary	en
dc.publisher.place	Calgary	en
dc.rights	University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subject	Veterinary Science
dc.subject.classification	hyperthermia	en_US
dc.subject.classification	VitalSense	en_US
dc.subject.classification	core temperature	en_US
dc.subject.classification	brown bears	en_US
dc.subject.classification	wildlife	en_US
dc.title	Evaluation of core temperature measurement and treatment of capture-related hyperthermia in anesthetized brown bears (Ursus arctos)
dc.type	master thesis
thesis.degree.grantor	University of Calgary
thesis.degree.name	Master of Science (MSc)
ucalgary.item.requestcopy	true