Epidemiological Assessment of Bipolar Disorder in Canada

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dc.contributor.advisorPatten, Scott
dc.contributor.authorMcDonald, Keltie
dc.date.accessioned2015-05-04T21:25:37Z
dc.date.available2015-06-22T07:00:48Z
dc.date.issued2015-05-04
dc.date.submitted2015en
dc.description.abstractObjective: The original aim of this thesis was to estimate the prevalence of bipolar disorder (BD) including bipolar I (BDI) and bipolar II (BDII) disorder subtypes, in Canada in 2012 and to characterize persons with BD in terms of demographic features, health status, and mental health service utilization. During the course of this thesis, a third objective emerged which was to examine some indicators of validity of the World Mental Health version of the World Health Organization Composite International Diagnostic Interview (WMH-CIDI) classifications of BD. Methods: Data were from the Canadian Community Health Survey-Mental Health (CCHS-MH; n=25,113) Interviews were based on the WMH-CIDI. The WMH-CIDI uses algorithms to determine the presence or absence of BD. Alternative classification methods were also considered. Using proportions and generalized linear modeling, I estimated prevalence of BD, examined agreement among different methods for classifying BD and described the epidemiology of BD according to the different classifications in terms of demographic features, health status and impact, and mental health service utilization. Results: According the WMH-CIDI algorithm, the prevalence of BDI and BDII in Canada in 2012 was 0.87% (95% CI 0.67% to 1.07%) and 0.57% (95% CI 0.44% to 0.71%), respectively. I observed a lack of congruence between WMH-CIDI defined and self-reported BD, and few people taking lithium were positive for BD on the WMH-CIDI, which raises concern about the validity of the WMH-CIDI’s assessment of BD. Conclusion: Prevalence estimates using the WMH-CIDI align with those reported in prior literature. However, existing algorithms used to diagnose BD in the WMH-CIDI appear to result in a large proportion of misclassification. Fully structured interviews may be inaccurate for assessing BD. Future research should aim to develop and evaluate new methods of identifying BD in the general population.en_US
dc.identifier.citationMcDonald, K. (2015). Epidemiological Assessment of Bipolar Disorder in Canada (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25924en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/25924
dc.identifier.urihttp://hdl.handle.net/11023/2242
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectEpidemiology
dc.subjectMental Health
dc.subject.classificationbipolar disorderen_US
dc.subject.classificationEpidemiologyen_US
dc.subject.classificationpsychiatric illnessen_US
dc.subject.classificationcross-sectional studiesen_US
dc.subject.classificationMental Healthen_US
dc.titleEpidemiological Assessment of Bipolar Disorder in Canada
dc.typemaster thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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