Application of the reservoir-wave approach to the renal circulation

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dc.contributor.advisorTyberg, John V.
dc.contributor.authorHandkamer, Kristen Claire
dc.date.accessioned2017-12-18T22:35:18Z
dc.date.available2017-12-18T22:35:18Z
dc.date.issued2012
dc.descriptionBibliography: p. 110-118en
dc.descriptionA few pages are in colour.en
dc.descriptionIncludes copy of animal protocol approval. Original copy with original Partial Copyright Licence.en
dc.description.abstractThe reservoir-wave approach provided the idea that systemic vascular resistance could be modeled as several component resistors arranged in series. The purpose of this investigation was to apply the reservoir-wave approach to the renal circulation and examine how a renal venous constriction (RVC) or a renal arterial infusion of vasoactive agents into one kidney altered conductance, P oo, and series resistances. Endothelin-1 and Angiotensin 11 reduced conductance to 39.6 ± 5.1 and 64.4 ± 4.3%; total renal resistance increased but arterial reservoir resistance decreased to 64.8 ± 6.3 and 80.0 ± 6.1 % of the control respectively. Endothelin-1 and Angiotensin II also increased Poo by 14.5 ± 2.7 and l 0.2 ± 3.6 mmHg, and the microcirculatory plus venous resistance to 187.2 ± 21.0 and 180.0 ± 35.8% ofthe control respectively. RVC increased conductance to I 12.3 ± 4.4% of the control, in apparent compensation. The reservoir-wave approach is applicable to the renal circulation and its use in subsequent investigations is warranted.
dc.format.extentxvi, 118 leaves : ill. ; 30 cm.en
dc.identifier.citationHandkamer, K. C. (2012). Application of the reservoir-wave approach to the renal circulation (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/4943en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/4943
dc.identifier.urihttp://hdl.handle.net/1880/105944
dc.language.isoeng
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.titleApplication of the reservoir-wave approach to the renal circulation
dc.typemaster thesis
thesis.degree.disciplineCardiovascular & Respiratory Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
ucalgary.thesis.accessionTheses Collection 58.002:Box 2109 627942979
ucalgary.thesis.notesUARCen
ucalgary.thesis.uarcreleaseyen
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