In vivo kinematic outcomes of cervical total disc arthroplasty using dual fluoroscopy: A longitudinal collective case study

Bangsboll, Emily Merle

In vivo kinematic outcomes of cervical total disc arthroplasty using dual fluoroscopy: A longitudinal collective case study

dc.contributor.advisor	Ronsky, Janet Lenore
dc.contributor.advisor	Swamy, Ganesh
dc.contributor.author	Bangsboll, Emily Merle
dc.contributor.committeemember	Roach, Koren Elaine
dc.contributor.committeemember	Duncan, Neil Alexander
dc.date	2025-02
dc.date.accessioned	2024-12-24T18:43:31Z
dc.date.available	2024-12-24T18:43:31Z
dc.date.issued	2024-12-19
dc.description.abstract	Intervertebral disc degeneration of the cervical spine is prevalent in aging adults with symptomatic cases often requiring surgical intervention. Cervical total disc arthroplasty (cTDA) is a surgical treatment for disc degeneration that aims to preserve natural motion of the spine and avoid adjacent segment degeneration. Despite low re-operation rates associated with cTDA, patient outcomes vary, and kinematic effects remain poorly understood. Understanding these effects via in vivo characterization could help address complications of cTDA and improve patient outcomes. This study implemented dual fluoroscopy to evaluate pre- and post-cTDA intervertebral rotations, translations, and endplate proximities to assess the impact of cTDA on in vivo cervical spine kinematics. Five asymptomatic control participants and two surgical participants undergoing cTDA were recruited. Participants underwent computed tomography and dual fluoroscopy imaging during dynamic movements. Model-based tracking matched subject-specific vertebral bone models to each dual fluoroscopy sequence with high accuracy (0.97 mm and 1.4°) and intervertebral rotations, translations, and bone-to-bone proximities were computed. The control pilot study verified the data collection and processing protocols yielded baseline data consistent with literature, although there was notable variability for some trials. Post-cTDA rotation patterns were similar to those of the controls, suggesting increased mobility at both treated and adjacent motion segments. Translations also increased post-cTDA, with some magnitudes exceeding one standard deviation above the control means, potentially indicating instability. Proximity measures indirectly described local disc height and illustrated the coupled motion patterns throughout movement, further emphasizing the value of three-dimensional in vivo kinematic approaches for studying the cervical spine. These kinematic measures have the potential to elucidate the complex coupled motion of the cervical spine post-cTDA and will be valuable for informing future artificial disc designs.
dc.identifier.citation	Bangsboll, E. (2024). In vivo kinematic outcomes of cervical total disc arthroplasty using dual fluoroscopy: a longitudinal collective case study (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca.
dc.identifier.uri	https://hdl.handle.net/1880/120299
dc.language.iso	en
dc.publisher.faculty	Graduate Studies
dc.publisher.institution	University of Calgary
dc.rights	University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subject	Dual fluoroscopy
dc.subject	Cervical total disc arthroplasty
dc.subject	Kinematics
dc.subject.classification	Engineering--Biomedical
dc.subject.classification	Medicine and Surgery
dc.title	In vivo kinematic outcomes of cervical total disc arthroplasty using dual fluoroscopy: A longitudinal collective case study
dc.type	master thesis
thesis.degree.discipline	Engineering – Biomedical
thesis.degree.grantor	University of Calgary
thesis.degree.name	Master of Science (MSc)
ucalgary.thesis.accesssetbystudent	I require a thesis withhold – I need to delay the release of my thesis due to a patent application, and other reasons outlined in the link above. I have/will need to submit a thesis withhold application.