The effects of hyperglycemia on vascular responses in individuals with obesity

Simple item page
dc.contributor.authorNewton, Janna
dc.contributor.authorSoares, Rogério Nogueira
dc.contributor.authorMurias, Juan M.
dc.date.accessioned2019-11-19T15:46:59Z
dc.date.available2019-11-19T15:46:59Z
dc.date.issued2019-01
dc.description.abstractObjective: To evaluate the acute effects of hyperglycemia on the vasculature of lean and obese individuals. Methods: Nine normal-weight (BMI 18.1 to 24.9 kg/m2) and nine individuals with obesity (BMI 30.0 to 39.9 kg/m2) underwent five vascular occlusion tests (VOT) at baseline, 30, 60, 90 and 120 min after ingesting 75 g of glucose diluted in 296 mL of water for an oral glucose tolerance test (OGTT). Flow-mediated dilation (FMD) was determined as the percent change in brachial artery diameter from baseline (mean of the 1 min diameter recordings prior cuff release) to peak in brachial artery diameter recorded during the 3 min reperfusion period. Results: Brachial %FMD was significantly (p < 0.05) reduced at 60 min (7.98 ± 4.33 %) after glucose ingestion when compared to pre (10.9 ± 3.99 %) in the obese group. Lean individuals showed no reduction in %FMD during hyperglycemia Conclusion: Hyperglycemia caused detrimental effects on brachial artery function at 60 min after glucose ingestion.en_US
dc.identifier.citationNewton, J., Soares, R. N., & Murias, J. M. (2017). "The effects of hyperglycemia on vascular responses in individuals with obesity". 12th Annual Students' Union Undergraduate Research Symposium, November 30, 2017. University of Calgary, Calgary, AB.en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/37254
dc.identifier.urihttp://hdl.handle.net/1880/111231
dc.publisher.departmentHuman Performance Laben_US
dc.publisher.facultyKinesiologyen_US
dc.titleThe effects of hyperglycemia on vascular responses in individuals with obesityen_US
dc.typeconference posteren_US
ucalgary.item.requestcopytrueen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
URS 2019.pdf
Size:
2.37 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.92 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Students' Union Undergraduate Research Symposium
Undergraduate Research & Publications