Electrocardiographic Parameters in the Assessment of Myocardial Fibrosis and Left Ventricular Systolic Function

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atmire.migration.oldid4789
dc.contributor.advisorExner, Derek V.
dc.contributor.authorNarous, Mariam
dc.contributor.committeememberAnderson, Todd J.
dc.contributor.committeememberFine, Nowell M.
dc.contributor.committeememberWhite, James A.
dc.date.accessioned2016-09-07T22:14:56Z
dc.date.available2016-09-07T22:14:56Z
dc.date.issued2016
dc.date.submitted2016en
dc.description.abstractAssessment of cardiac structure and function is central to the care of patients with heart disease. Cardiac magnetic resonance (CMR) is the gold standard for such assessment, however it is expensive and oftentimes not readily accessible. We sought to evaluate the utility of electrocardiographic (ECG) and impedance-based parameters in estimating the amount of myocardial scar, left ventricular (LV) systolic function and myocardial deformation. Consecutive patients (n = 241; 42% female; mean age 55 years) undergoing clinical CMR and ECG assessments were recruited. ECG analysis was performed manually, using both the Modified Selvester Score (MSS) and the presence of fractionated QRS (fQRS) signals, and impedance testing using the Non-Invasive Cardiac System (NICaS). While MCS was of value, neither fQRS nor NICaS meaningfully predicted scar extent, LV systolic function. Or the amount of myocardial deformation. These results support additional investigation of the utility of the MSS in estimating cardiac structure and function among patients in whom cardiac imaging is clinically indicated.en_US
dc.identifier.citationNarous, M. (2016). Electrocardiographic Parameters in the Assessment of Myocardial Fibrosis and Left Ventricular Systolic Function (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25858en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/25858
dc.identifier.urihttp://hdl.handle.net/11023/3274
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectMedicine and Surgery
dc.titleElectrocardiographic Parameters in the Assessment of Myocardial Fibrosis and Left Ventricular Systolic Function
dc.typemaster thesis
thesis.degree.disciplineCardiovascular & Respiratory Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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