Dynamic Control of Gas Chromatographic Selectivity during the Analysis of Organic Bases

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dc.contributor.authorDarko, Ernest
dc.contributor.authorThurbide, Kevin B.
dc.date.accessioned2019-07-02T17:56:20Z
dc.date.available2019-07-02T17:56:20Z
dc.date.issued2019-05-06
dc.description.abstractA novel method for controlling selectivity during the gas chromatographic (GC) analysis of organic bases is presented. The technique employs tandem stainless steel capillary columns, each coated with a pH adjusted water stationary phase. The first is a 0.5 m trap column coated with a pH 2.2 phase, while the second is an 11 m analytical column coated with a pH 11.4 phase. The first column traps basic analytes from injected samples, while the remaining components continue to elute and separate. Then, upon injection of a volatile aqueous ammonia solution, the basic analytes are released as desired to the analytical column where they are separated and analyzed. Separations are quite reproducible and demonstrate an average RSD of 1.2% for analyte retention times in consecutive trials. Using this approach, the retention of such analytes can be readily controlled and they can be held in the system for periods of up to 1 h without significant erosion of peak shape. As such, it can provide considerable control over analyte selectivity and resolution compared to conventional separations. Further, by employing a third conventional GC column to the series, both traditional hydrocarbon and enhanced organic base separations can be performed. The method is applied to the analysis of complex mixtures, such as gasoline, and much less matrix interference is observed as a result. The findings indicate that this approach could be a useful alternative for analyzing such samplesen_US
dc.description.grantingagencyNatural Sciences and Engineering Research Council - Collaborative Research & Development Granten_US
dc.identifier.citationDarko, E., & Thurbide, K. B. (2019). Dynamic control of gas chromatographic selectivity during the analysis of organic bases. Analytical Chemistry, doi:10.1021/acs.analchem.9b00703en_US
dc.identifier.doi10.1021/acs.analchem.9b00703en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/36673
dc.identifier.issn0003-2700
dc.identifier.issn1520-6882
dc.identifier.urihttp://hdl.handle.net/1880/110547
dc.language.isoengen_US
dc.publisherScopusen_US
dc.publisher.departmentChemistryen_US
dc.publisher.facultyScienceen_US
dc.publisher.hasversionPost-printen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.policyhttps://www.elsevier.com/solutions/scopus/how-scopus-works/content/content-policy-and-selectionen_US
dc.rightsUnless otherwise indicated, this material is protected by copyright and has been made available with authorization from the copyright owner. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.en_US
dc.subjectgas chromatographyen_US
dc.subjectwater stationary phaseen_US
dc.subjecttrap columnen_US
dc.subjectselectivityen_US
dc.subjectorganic basesen_US
dc.titleDynamic Control of Gas Chromatographic Selectivity during the Analysis of Organic Basesen_US
dc.typeunknown
ucalgary.item.requestcopytrueen_US
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