Evolution of group II introns

Simple item page
dc.contributor.authorZimmerly, Steven
dc.contributor.authorSemper, Cameron
dc.date.accessioned2016-04-15T22:41:02Z
dc.date.available2016-04-15T22:41:02Z
dc.date.issued2015
dc.description.abstractPresent in the genomes of bacteria and eukaryotic organelles, group II introns are an ancient class of ribozymes and retroelements that are believed to have been the ancestors of nuclear pre-mRNA introns. Despite long-standing speculation, there is limited understanding about the actual pathway by which group II introns evolved into eukaryotic introns. In this review, we focus on the evolution of group II introns themselves. We describe the different forms of group II introns known to exist in nature and then address how these forms may have evolved to give rise to spliceosomal introns and other genetic elements. Finally, we summarize the structural and biochemical parallels between group II introns and the spliceosome, including recent data that strongly support their hypothesized evolutionary relationship.en_US
dc.description.refereedYesen_US
dc.identifier.citationZimmerly, S., & Semper, C. (2015). Evolution of group II introns. Mobile DNA, 6(1), 7.en_US
dc.identifier.doi10.1186/s13100-015-0037-5
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/35160
dc.identifier.urihttp://hdl.handle.net/1880/51149
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.publisher.departmentBiological Sciencesen_US
dc.publisher.facultyScienceen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.urlhttp://mobilednajournal.biomedcentral.com/articles/10.1186/s13100-015-0037-5en_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectRibozymeen_US
dc.subjectRetroelementen_US
dc.subjectSpliceosomeen_US
dc.subjectMolecular evolutionen_US
dc.subjectMobile DNAen_US
dc.titleEvolution of group II intronsen_US
dc.typejournal article
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
gpII evolution review.pdf
Size:
1.65 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.84 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Science Research & Publications