Using the ages and stages questionnaire in the general population as a measure for identifying children not at risk of a neurodevelopmental disorder

dc.contributor.authorLamsal, Ramesh
dc.contributor.authorDutton, Daniel J.
dc.contributor.authorZwicker, Jennifer D.
dc.date.accessioned2018-04-09T19:56:54Z
dc.date.available2018-04-09T19:56:54Z
dc.date.issued2018-04-03
dc.description.abstractBackground Early detection of neurodevelopmental disorders (NDDs) enables access to early interventions for children. We assess the Ages and Stages Questionnaire (ASQ)’s ability to identify children with a NDD in population data. Method Children 4 to 5 years old in the National Longitudinal Survey of Children and Youth (NLSCY) from cycles 5 to 8 were included. The sensitivity, specificity, positive and negative predictive values were calculated for the ASQ at 24, 27, 30, 33, 36 and 42 months. Fixed effects regression analyses assessed longitudinal associations between domain scores and child age. Results Specificity for the ASQ was high with 1SD or 2SD cutoffs, indicating good accuracy in detecting children who will not develop a NDD, however the sensitivity varied over time points and cut-offs. Sensitivity for the 1 SD cutoff at 24 months was above the recommended value of 70% for screening. Differences in ASQ domains scores between children with and without NDD increases with age. Conclusions The high specificity and negative predictive values of the ASQ support its use in identifying children who are not at the risk of developing a NDD. The capacity of the ASQ to identify children with a NDD in the general population is limited except for the ASQ-24 months with 1SD and can be used to identify children at risk of NDD.en_US
dc.identifier.citationLamsal, R., Dutton, D. J., & Zwicker, J. D. (2018). Using the ages and stages questionnaire in the general population as a measure for identifying children not at risk of a neurodevelopmental disorder. BMC pediatrics, 18(1), 122.en_US
dc.identifier.doihttps://doi.org/10.1186/s12887-018-1105-zen_US
dc.identifier.urihttp://hdl.handle.net/1880/106481
dc.identifier.urihttps://doi.org/10.11575/PRISM/46008
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.publisher.facultyGraduate Studiesen_US
dc.publisher.hasversionPublisher's versionen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.policyhttps://www.biomedcentral.com/getpublished/copyright-and-licenseen_US
dc.rightsUnless otherwise indicated, this material is protected by copyright and has been made available with authorization from the copyright owner. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.subjectAges and stages questionnaire (ASQ)Neurodevelopmental disabilitiesEarly identificationEarly interventionScreeningen_US
dc.titleUsing the ages and stages questionnaire in the general population as a measure for identifying children not at risk of a neurodevelopmental disorderen_US
dc.typejournal article
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